Matches in SemOpenAlex for { <https://semopenalex.org/work/W939543367> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W939543367 endingPage "539" @default.
- W939543367 startingPage "532" @default.
- W939543367 abstract "The antitumor properties of the anthracyclines, including adriamycin, which shows the broadest activity clinically, correlate with their capacity to bind intercalatively to duplex DNA, although other cellular effects appear to be significant. The administration of adriamycin and daunorubicin is accompanied by severe risk of cardiotoxicity. Growing evidence indicates that this side effect may be related to factors, including the accumulation of the drug in cardiac tissue; reductive enzymatic activation at the chromophore, which in the presence of oxygen produces reactive oxygen species; concomitant oxidative damage of membrane lipids; and the diminished levels in the heart of enzymes, which effect protection against cellular oxidative lesions. Assays designed to detect and quantify the production of individual reactive oxygen species from activated anthracyclines may, therefore, be useful in comparing drugs designed to alleviate this serious clinical limitation of cardiotoxicity." @default.
- W939543367 created "2016-06-24" @default.
- W939543367 creator A5023279335 @default.
- W939543367 date "1984-01-01" @default.
- W939543367 modified "2023-09-27" @default.
- W939543367 title "[70] Ethidium binding assay for reactive oxygen species generated from reductively activated adriamycin (Doxorubicin)" @default.
- W939543367 cites W1517318768 @default.
- W939543367 cites W1590106897 @default.
- W939543367 cites W1920198420 @default.
- W939543367 cites W1969478695 @default.
- W939543367 cites W1992669360 @default.
- W939543367 cites W2008076873 @default.
- W939543367 cites W2011682937 @default.
- W939543367 cites W2019664243 @default.
- W939543367 cites W2037236039 @default.
- W939543367 cites W2052444490 @default.
- W939543367 cites W2057562105 @default.
- W939543367 cites W2060999200 @default.
- W939543367 cites W2064177299 @default.
- W939543367 cites W2067416973 @default.
- W939543367 cites W2091789486 @default.
- W939543367 cites W2119144097 @default.
- W939543367 cites W2120353772 @default.
- W939543367 cites W2126196847 @default.
- W939543367 cites W2149514469 @default.
- W939543367 cites W2160976623 @default.
- W939543367 cites W2235940902 @default.
- W939543367 doi "https://doi.org/10.1016/s0076-6879(84)05073-4" @default.
- W939543367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6328204" @default.
- W939543367 hasPublicationYear "1984" @default.
- W939543367 type Work @default.
- W939543367 sameAs 939543367 @default.
- W939543367 citedByCount "17" @default.
- W939543367 countsByYear W9395433672015 @default.
- W939543367 countsByYear W9395433672022 @default.
- W939543367 crossrefType "book-chapter" @default.
- W939543367 hasAuthorship W939543367A5023279335 @default.
- W939543367 hasConcept C178790620 @default.
- W939543367 hasConcept C181199279 @default.
- W939543367 hasConcept C185592680 @default.
- W939543367 hasConcept C2776151105 @default.
- W939543367 hasConcept C2776694085 @default.
- W939543367 hasConcept C2778233292 @default.
- W939543367 hasConcept C2781021840 @default.
- W939543367 hasConcept C2781303535 @default.
- W939543367 hasConcept C29730261 @default.
- W939543367 hasConcept C48349386 @default.
- W939543367 hasConcept C540031477 @default.
- W939543367 hasConcept C54355233 @default.
- W939543367 hasConcept C55493867 @default.
- W939543367 hasConcept C57600042 @default.
- W939543367 hasConcept C86803240 @default.
- W939543367 hasConcept C98274493 @default.
- W939543367 hasConceptScore W939543367C178790620 @default.
- W939543367 hasConceptScore W939543367C181199279 @default.
- W939543367 hasConceptScore W939543367C185592680 @default.
- W939543367 hasConceptScore W939543367C2776151105 @default.
- W939543367 hasConceptScore W939543367C2776694085 @default.
- W939543367 hasConceptScore W939543367C2778233292 @default.
- W939543367 hasConceptScore W939543367C2781021840 @default.
- W939543367 hasConceptScore W939543367C2781303535 @default.
- W939543367 hasConceptScore W939543367C29730261 @default.
- W939543367 hasConceptScore W939543367C48349386 @default.
- W939543367 hasConceptScore W939543367C540031477 @default.
- W939543367 hasConceptScore W939543367C54355233 @default.
- W939543367 hasConceptScore W939543367C55493867 @default.
- W939543367 hasConceptScore W939543367C57600042 @default.
- W939543367 hasConceptScore W939543367C86803240 @default.
- W939543367 hasConceptScore W939543367C98274493 @default.
- W939543367 hasLocation W9395433671 @default.
- W939543367 hasLocation W9395433672 @default.
- W939543367 hasOpenAccess W939543367 @default.
- W939543367 hasPrimaryLocation W9395433671 @default.
- W939543367 hasRelatedWork W1967234838 @default.
- W939543367 hasRelatedWork W2000325978 @default.
- W939543367 hasRelatedWork W2056386224 @default.
- W939543367 hasRelatedWork W2066961318 @default.
- W939543367 hasRelatedWork W2757190129 @default.
- W939543367 hasRelatedWork W2786814199 @default.
- W939543367 hasRelatedWork W3094765933 @default.
- W939543367 hasRelatedWork W3186953429 @default.
- W939543367 hasRelatedWork W3204282722 @default.
- W939543367 hasRelatedWork W4281784617 @default.
- W939543367 isParatext "false" @default.
- W939543367 isRetracted "false" @default.
- W939543367 magId "939543367" @default.
- W939543367 workType "book-chapter" @default.