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- W942248731 abstract "目的:探讨谷胱甘肽过氧化物酶模拟物2-TeCD对H2O2诱导SH—SY5Y细胞发生凋亡的影响。方法:用H2嘎和2-TeCD分组作用于人神经母细胞瘤SH—SY5Y细胞,检测对细胞的存活率、凋亡率、细胞相对活性、凋亡相关基因Bax、Bcl一2和相关蛋白UspTO、caspase-3的表达。结果:2-TeCD可明显提高飓(=)2损伤SH~SY5Y细胞的细胞存活率和细胞相对活性;下调促进凋亡基因Bax和上调抑制凋亡基因Bcl-2;降低caspase-3的表达量而对Hsp70无较大影响。结论:2-TeCD对H202诱发的SH—SY5Y细胞凋亡具有明显的抑制作用,可成为潜在的抗氧化药物。" @default.
- W942248731 created "2016-06-24" @default.
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- W942248731 date "2012-01-01" @default.
- W942248731 modified "2023-09-23" @default.
- W942248731 title "谷胱甘肽过氧化物酶模拟物2-TeCD对过氧化氢诱导人成神经母细胞瘤SH-SY5Y细胞凋亡的抑制" @default.
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