Matches in SemOpenAlex for { <https://semopenalex.org/work/W942620207> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W942620207 endingPage "596" @default.
- W942620207 startingPage "585" @default.
- W942620207 abstract "The effect of estradiol - 17β (E2)treatment on the pituitary-thyroidal axis has been investigated in female Japanese eels in seawater. The eels were injected with 1 mg/kg body weight (BW)weekly for two to eight weeks; another group was treated with 5 mg/kg BW weekly for eight weeks and sacrificed three days after the last injection. In the pituitary, using RT- PCR system, the thyroid stimulating hormone β subunit mRNA (TSHβ mRNA) level is slowly increased in the low-dose E2 treatment group. A significant increase in values occurred after eight weeks E2 injections. The histological structure of the thyroid follicles suggests a hypo-activity as shown by a reduced epithelial cell height in eels injected with E2 after six and eight times, and eventually reached a minimum level after eight weeks. Using radioimmunoassay of thyroxine (T4), triiodothyronine (T3) in the serum, a slowly decrease of both hormones is demonstrated. On the other hand, the TSHβ mRNA level is significantly increased from initial in the high-dose E2 treatment group. The histological structure of the thyroid follicles suggests a hypoactivity, and a sharp decrease of the both hormones is also indicated. These data suggest that the expression of TSHβ mRNA level is increased and thyroid hormone release is depressed by E2, the effects depend upon E2 injection period and dose. Furthermore, E2 could not directly influence the TSHβ mRNA expression and, TSH transcription might be controlled by a negative feedback of thyroid hormone." @default.
- W942620207 created "2016-06-24" @default.
- W942620207 creator A5002529010 @default.
- W942620207 creator A5002626175 @default.
- W942620207 creator A5034593993 @default.
- W942620207 creator A5035599968 @default.
- W942620207 creator A5042767084 @default.
- W942620207 creator A5057559744 @default.
- W942620207 creator A5063076608 @default.
- W942620207 creator A5063554109 @default.
- W942620207 date "2001-01-01" @default.
- W942620207 modified "2023-09-24" @default.
- W942620207 title "Effect of estradiol- 17β on pituitary-thyroidal axis of Japanese eel (Anguilla japonica )" @default.
- W942620207 hasPublicationYear "2001" @default.
- W942620207 type Work @default.
- W942620207 sameAs 942620207 @default.
- W942620207 citedByCount "1" @default.
- W942620207 crossrefType "journal-article" @default.
- W942620207 hasAuthorship W942620207A5002529010 @default.
- W942620207 hasAuthorship W942620207A5002626175 @default.
- W942620207 hasAuthorship W942620207A5034593993 @default.
- W942620207 hasAuthorship W942620207A5035599968 @default.
- W942620207 hasAuthorship W942620207A5042767084 @default.
- W942620207 hasAuthorship W942620207A5057559744 @default.
- W942620207 hasAuthorship W942620207A5063076608 @default.
- W942620207 hasAuthorship W942620207A5063554109 @default.
- W942620207 hasConcept C113214860 @default.
- W942620207 hasConcept C126322002 @default.
- W942620207 hasConcept C134018914 @default.
- W942620207 hasConcept C176685330 @default.
- W942620207 hasConcept C185592680 @default.
- W942620207 hasConcept C2777886399 @default.
- W942620207 hasConcept C2778288131 @default.
- W942620207 hasConcept C526584372 @default.
- W942620207 hasConcept C71315377 @default.
- W942620207 hasConcept C71924100 @default.
- W942620207 hasConcept C86803240 @default.
- W942620207 hasConceptScore W942620207C113214860 @default.
- W942620207 hasConceptScore W942620207C126322002 @default.
- W942620207 hasConceptScore W942620207C134018914 @default.
- W942620207 hasConceptScore W942620207C176685330 @default.
- W942620207 hasConceptScore W942620207C185592680 @default.
- W942620207 hasConceptScore W942620207C2777886399 @default.
- W942620207 hasConceptScore W942620207C2778288131 @default.
- W942620207 hasConceptScore W942620207C526584372 @default.
- W942620207 hasConceptScore W942620207C71315377 @default.
- W942620207 hasConceptScore W942620207C71924100 @default.
- W942620207 hasConceptScore W942620207C86803240 @default.
- W942620207 hasIssue "4" @default.
- W942620207 hasLocation W9426202071 @default.
- W942620207 hasOpenAccess W942620207 @default.
- W942620207 hasPrimaryLocation W9426202071 @default.
- W942620207 hasRelatedWork W1965986236 @default.
- W942620207 hasRelatedWork W1982931688 @default.
- W942620207 hasRelatedWork W1986051853 @default.
- W942620207 hasRelatedWork W1999193862 @default.
- W942620207 hasRelatedWork W2021222081 @default.
- W942620207 hasRelatedWork W2033913582 @default.
- W942620207 hasRelatedWork W2045124713 @default.
- W942620207 hasRelatedWork W2057628154 @default.
- W942620207 hasRelatedWork W2068037207 @default.
- W942620207 hasRelatedWork W2085220827 @default.
- W942620207 hasRelatedWork W2088497706 @default.
- W942620207 hasRelatedWork W2096397790 @default.
- W942620207 hasRelatedWork W2105215289 @default.
- W942620207 hasRelatedWork W2116325003 @default.
- W942620207 hasRelatedWork W2126834795 @default.
- W942620207 hasRelatedWork W2141656532 @default.
- W942620207 hasRelatedWork W2174449017 @default.
- W942620207 hasRelatedWork W2394627092 @default.
- W942620207 hasRelatedWork W2410492050 @default.
- W942620207 hasRelatedWork W2415473350 @default.
- W942620207 isParatext "false" @default.
- W942620207 isRetracted "false" @default.
- W942620207 magId "942620207" @default.
- W942620207 workType "article" @default.