Matches in SemOpenAlex for { <https://semopenalex.org/work/W942708085> ?p ?o ?g. }
- W942708085 abstract "Publisher Summary Thrombolytic therapy has the ability to restore blood flow in most patients with an occluded coronary artery, but many problems remain. For instance, not all patients reperfuse in response to the thrombolytics, and of those who do undergo successful coronary thrombolysis, an unacceptable fraction will experience acute reocclusion. The factors related to initial thrombosis and rethrombosis following thrombolysis are complex but involve the interaction of blood platelets, the coagulation cascade, and the endogenous fibrinolytic capacity of the patient. Thus, platelet aggregation, blood coagulation, and endogenous fibrinolysis represent viable drug discovery targets as a means to improve the morbidity and mortality associated with myocardial infarction. This chapter discusses the new drug discovery targets related to the inhibition of platelet aggregation, interruption of the coagulation cascade, and modulation of the endogenous fibrinolytic system." @default.
- W942708085 created "2016-06-24" @default.
- W942708085 creator A5002085315 @default.
- W942708085 date "1991-01-01" @default.
- W942708085 modified "2023-09-23" @default.
- W942708085 title "Chapter 10. Emerging Drug Discovery Targets in Thrombosis and Coagulation" @default.
- W942708085 cites W1538887755 @default.
- W942708085 cites W1555943967 @default.
- W942708085 cites W1568427873 @default.
- W942708085 cites W1569353770 @default.
- W942708085 cites W1599049360 @default.
- W942708085 cites W1600823549 @default.
- W942708085 cites W1601949152 @default.
- W942708085 cites W1696947947 @default.
- W942708085 cites W1701123637 @default.
- W942708085 cites W1761018113 @default.
- W942708085 cites W1969632860 @default.
- W942708085 cites W1974228025 @default.
- W942708085 cites W1979698812 @default.
- W942708085 cites W1981438065 @default.
- W942708085 cites W1984119855 @default.
- W942708085 cites W1984323352 @default.
- W942708085 cites W1987275831 @default.
- W942708085 cites W1991243300 @default.
- W942708085 cites W2012171708 @default.
- W942708085 cites W2013547341 @default.
- W942708085 cites W2017575247 @default.
- W942708085 cites W2018235565 @default.
- W942708085 cites W2020093967 @default.
- W942708085 cites W2025768989 @default.
- W942708085 cites W2027451228 @default.
- W942708085 cites W2030087792 @default.
- W942708085 cites W2030328556 @default.
- W942708085 cites W2034816682 @default.
- W942708085 cites W2035199742 @default.
- W942708085 cites W2035307463 @default.
- W942708085 cites W2038681046 @default.
- W942708085 cites W2045202161 @default.
- W942708085 cites W2045384699 @default.
- W942708085 cites W2046027264 @default.
- W942708085 cites W2047122746 @default.
- W942708085 cites W2053350675 @default.
- W942708085 cites W2053913287 @default.
- W942708085 cites W2054050090 @default.
- W942708085 cites W2054098499 @default.
- W942708085 cites W2056505207 @default.
- W942708085 cites W2060297306 @default.
- W942708085 cites W2062185761 @default.
- W942708085 cites W2062273793 @default.
- W942708085 cites W2063001950 @default.
- W942708085 cites W2063790836 @default.
- W942708085 cites W2068877244 @default.
- W942708085 cites W2070704281 @default.
- W942708085 cites W2078824617 @default.
- W942708085 cites W2079487514 @default.
- W942708085 cites W2079845152 @default.
- W942708085 cites W2085129667 @default.
- W942708085 cites W2085304257 @default.
- W942708085 cites W2086139532 @default.
- W942708085 cites W2087299903 @default.
- W942708085 cites W2093491931 @default.
- W942708085 cites W2093960165 @default.
- W942708085 cites W2097908856 @default.
- W942708085 cites W2117030548 @default.
- W942708085 cites W2140639517 @default.
- W942708085 cites W2163687471 @default.
- W942708085 cites W2163995157 @default.
- W942708085 cites W2169273710 @default.
- W942708085 cites W217496567 @default.
- W942708085 cites W2266038146 @default.
- W942708085 cites W2293220210 @default.
- W942708085 cites W2323292981 @default.
- W942708085 cites W2336267479 @default.
- W942708085 cites W2340828684 @default.
- W942708085 cites W2396711716 @default.
- W942708085 cites W2399446904 @default.
- W942708085 cites W2416111824 @default.
- W942708085 cites W2417963531 @default.
- W942708085 cites W2430781207 @default.
- W942708085 cites W2465519329 @default.
- W942708085 cites W2519220328 @default.
- W942708085 cites W278766787 @default.
- W942708085 cites W281257934 @default.
- W942708085 cites W292647304 @default.
- W942708085 cites W93102090 @default.
- W942708085 doi "https://doi.org/10.1016/s0065-7743(08)61197-5" @default.
- W942708085 hasPublicationYear "1991" @default.
- W942708085 type Work @default.
- W942708085 sameAs 942708085 @default.
- W942708085 citedByCount "4" @default.
- W942708085 crossrefType "book-chapter" @default.
- W942708085 hasAuthorship W942708085A5002085315 @default.
- W942708085 hasConcept C126322002 @default.
- W942708085 hasConcept C164705383 @default.
- W942708085 hasConcept C16613235 @default.
- W942708085 hasConcept C2776825266 @default.
- W942708085 hasConcept C2777377995 @default.
- W942708085 hasConcept C2778382381 @default.
- W942708085 hasConcept C2779581417 @default.
- W942708085 hasConcept C2780035454 @default.