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• W94317274 abstract "Sleep restriction increases white blood cells, mainly neutrophil count, in young healthy men: A pilot study Karim Zouaoui Boudjeltia2, Brice Faraut1,2, Patricia Stenuit1, Maria José Esposito1,2, Michal Dyzma1,2, Dany Brohée2, Jean Ducobu2, Michel Vanhaeverbeek2, Myriam Kerkhofs1,21Sleep Laboratory; 2Laboratory of Experimental Medicine (ULB 222 Unit), CHU de Charleroi Vésale Hospital, Université Libre de Bruxelles, Montigny-le-Tilleul, BelgiumObjectives: This study examines the effects of sleep restricted to four hours for three consecutive nights on blood parameters, known to be associated with cardiovascular risk, in young healthy men.Material and methods: Eight young healthy men (age 24.5 ± 3.3 years) were studied in the sleep restricted group. Nine young healthy men (age 24 ± 2 years) were included in the control group and spent the days and nights in the sleep lab, while sleeping eight hours/night. One baseline night was followed by three nights of sleep restriction to four hours and by one recovery night of eight hours. Blood samplings were performed after the baseline night and after the third night of sleep restriction or without restriction for the control group.Results: A significant increase in white blood cells (WBC) (5.79 ± 1.05 vs. 6.89 ± 1.31 103 cell/µl, p = 0.03), and neutrophils (3.17 ± 0.69 vs 4.24 ± 0.97 103 cell/µl, p = 0.01) was observed after the third night of sleep restriction. Other blood parameters were not affected. No significant variation was observed in the control group.Conclusion: Sleep restriction affected WBC count, mainly neutrophils, considered as risk factor for cardiovascular disease. Stress induced by the short term sleep restriction could be involved in this observation.Keywords: sleep restriction, men, cardiovascular risk, cholesterol, neutrophils" @default.
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• W94317274 date "2008-12-01" @default.
• W94317274 modified "2023-10-17" @default.
• W94317274 title "Sleep restriction increases white blood cells, mainly neutrophil count, in young healthy men: A pilot study" @default.
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• W94317274 doi "https://doi.org/10.2147/vhrm.s3934" @default.
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