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- W944587166 abstract "The carefully run RCTs CHARM (2003), Val-HeFT (2001), and TRANSCEND (2008) did not show a decrease in total mortality in heart failure (HF) subjects (see Chaps. 4 and 12). This surprising finding was observed in patients intolerant to ACE inhibitor administration. It is abundantly clear that ARBs are not as effective as ACE inhibitor therapy for HF, hypertension, or stroke. The salutary effects of ARBs are probably less than that observed with digoxin, yet these agents are used widely and excessively. In Val-HeFT valsartan when combined with a beta-blocker caused significantly more cardiac events." @default.
- W944587166 created "2016-06-24" @default.
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- W944587166 date "2014-10-04" @default.
- W944587166 modified "2023-10-18" @default.
- W944587166 title "Heart Failure Controversies" @default.
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- W944587166 doi "https://doi.org/10.1007/978-1-61779-962-4_13" @default.
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