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- W944804874 abstract "Ghrelin 首先从胃被分泌并且在吃行为和重量规定的协作被含有。Ghrelin 也在胃的粘膜防卫的机制起一个必要作用。因此,澄清哪个疾病首先在血浆 ghrelin 集中影响变化是重要的。Helicobacter pylori (H pylori ) 感染涉及胃炎的致病,胃并且十二指肠溃疡,胃的癌,和联系 mucosa 的淋巴组织淋巴瘤。H pylori 根除与体重变化有关。比较,在胃粘膜生产房间的 ghrelin 的感染的 H pylori 和有身体质量索引的正常的否定题目,血浆 ghrelin 集中,胃的 ghrelin mRNA,和数字在 H pylori 是显著地更低的比感染了题目在 H pylori 否定的控制。血浆 ghrelin 集中与胃的萎缩的前进减少。与 H pylori 感染导致的萎缩性胃炎联合的损害胃的 ghrelin 生产在血浆 ghrelin 集中说明减少。然而,到全部的 ghrelin 层次的血浆酰 ated ghrelin 的比率比在健康题目在有长期的萎缩性胃炎的病人是更高的。这可以源于血浆的补偿增加响应胃的萎缩的活跃 ghrelin 集中。在 H pylori 根除以后,胃的 preproghrelin mRNA 表示被增加将近在大多数情况中的 4 褶层。然而,在 H pylori 痊愈没与胃的 ghrelin 生产被联系前后,在血浆 ghrelin 集中变化。血浆 ghrelin 变化相反地与体重变化和起始的血浆 ghrelin 层次被相关。" @default.
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- W944804874 date "2008-01-01" @default.
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- W944804874 title "Ghrelin and Helicobacterpylori infection" @default.
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