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- W946442912 abstract "In the interplay between cellular signal transduction and the ubiquitin system, the latter was often thought of as lying near the bottom of the signaling cascade, in the role of executioner of phosphorylated proteins, merely carrying out the verdict of the kinases. However, not only instances where the ubiquitination complex is itself the recipient of the signal has been seen, but in one case so far, that of the NFκB pathway, the ubiquitin system can even interfere with signaling by directly modulating the activity of kinases. It is likely that the NFκB pathway, which exemplifies the versatility of the ubiquitin system, will serve as a useful paradigm for the role of the ubiquitin system in other signal transduction pathways." @default.
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- W946442912 date "2003-01-01" @default.
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- W946442912 title "Proteasome/Ubiquitination" @default.
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- W946442912 doi "https://doi.org/10.1016/b978-012124546-7/50652-5" @default.
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