FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W947780285> ?p ?o ?g. }

• W947780285 endingPage "309" @default.
• W947780285 startingPage "283" @default.
• W947780285 abstract "This chapter describes various methods that are used to measure absolute and relative affinities, to pinpoint the difficulties and errors inherent in some of them, and to attempt to rationalize their solution. The heterogeneous nature of antibodies in antisera makes meaningful measurements of affinity very difficult. Different values of association constant and viral valency can be generated for a single antiserum from experiments carried out at different antibody dilutions, and particular antibody valencies cannot be assumed. Nevertheless, the Scatchard form of analysis can yield useful information about the range of affinities within an antibody population and under appropriate conditions can produce accurate estimates of virus valency. Solid-phase measurements have considerably simplified the mechanical operations of antibody/antigen assays. They can, however, be subject to errors because of limiting diffusion rates at low antibody concentration, conformational distortion of coated antigen, artificial increases of avidity at high coating concentrations, and differential binding of secondary label. Comparative assays can provide useful estimates of relative affinities if they are used in the sensitive range for any particular antibody-antigen assay system. Solid-phase coating densities critically affect the sensitivities of these assays to relative affinities. Monoclonal antibodies pose particular problems because of their individual characteristics in terms of affinity, behavior in different physical and chemical environments, and detectability with secondary label. These factors affect the suitability of different types of assay for detection of relative affinities." @default.
• W947780285 created "2016-06-24" @default.
• W947780285 creator A5002500313 @default.
• W947780285 date "1988-01-01" @default.
• W947780285 modified "2023-10-16" @default.
• W947780285 title "Measurement of the Affinity of Antiviral Antibodies" @default.
• W947780285 cites W1011888941 @default.
• W947780285 cites W1524628722 @default.
• W947780285 cites W1552402287 @default.
• W947780285 cites W1576664115 @default.
• W947780285 cites W1668543300 @default.
• W947780285 cites W1675915938 @default.
• W947780285 cites W1737146007 @default.
• W947780285 cites W190667819 @default.
• W947780285 cites W1966756198 @default.
• W947780285 cites W1968307799 @default.
• W947780285 cites W1983649348 @default.
• W947780285 cites W1984412128 @default.
• W947780285 cites W1984416131 @default.
• W947780285 cites W1984493518 @default.
• W947780285 cites W1985405536 @default.
• W947780285 cites W1985589967 @default.
• W947780285 cites W1989651677 @default.
• W947780285 cites W1998831848 @default.
• W947780285 cites W2002687981 @default.
• W947780285 cites W2004593200 @default.
• W947780285 cites W2006356344 @default.
• W947780285 cites W2006727482 @default.
• W947780285 cites W2007185872 @default.
• W947780285 cites W2010518301 @default.
• W947780285 cites W2011500156 @default.
• W947780285 cites W2014270552 @default.
• W947780285 cites W2020723775 @default.
• W947780285 cites W2031600268 @default.
• W947780285 cites W2034795719 @default.
• W947780285 cites W2038588500 @default.
• W947780285 cites W2041428851 @default.
• W947780285 cites W2043799721 @default.
• W947780285 cites W2044577630 @default.
• W947780285 cites W2048787397 @default.
• W947780285 cites W2050563013 @default.
• W947780285 cites W2056212959 @default.
• W947780285 cites W2061099789 @default.
• W947780285 cites W2062740562 @default.
• W947780285 cites W2063329479 @default.
• W947780285 cites W2071138716 @default.
• W947780285 cites W2086903827 @default.
• W947780285 cites W2087847210 @default.
• W947780285 cites W2091587236 @default.
• W947780285 cites W2095546376 @default.
• W947780285 cites W2106374593 @default.
• W947780285 cites W2111278962 @default.
• W947780285 cites W2111659287 @default.
• W947780285 cites W2114964797 @default.
• W947780285 cites W2116486692 @default.
• W947780285 cites W2132813133 @default.
• W947780285 cites W2142607266 @default.
• W947780285 cites W2215802797 @default.
• W947780285 cites W2324754530 @default.
• W947780285 cites W2419523978 @default.
• W947780285 cites W2799827436 @default.
• W947780285 cites W281973525 @default.
• W947780285 cites W4321829154 @default.
• W947780285 doi "https://doi.org/10.1016/s0065-3527(08)60521-7" @default.
• W947780285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3046256" @default.
• W947780285 hasPublicationYear "1988" @default.
• W947780285 type Work @default.
• W947780285 sameAs 947780285 @default.
• W947780285 citedByCount "21" @default.
• W947780285 countsByYear W9477802852014 @default.
• W947780285 countsByYear W9477802852016 @default.
• W947780285 crossrefType "book-chapter" @default.
• W947780285 hasAuthorship W947780285A5002500313 @default.
• W947780285 hasConcept C142724271 @default.
• W947780285 hasConcept C147483822 @default.
• W947780285 hasConcept C159654299 @default.
• W947780285 hasConcept C170493617 @default.
• W947780285 hasConcept C179223381 @default.
• W947780285 hasConcept C184112429 @default.
• W947780285 hasConcept C185592680 @default.
• W947780285 hasConcept C203014093 @default.
• W947780285 hasConcept C204787440 @default.
• W947780285 hasConcept C2780283098 @default.
• W947780285 hasConcept C2908647359 @default.
• W947780285 hasConcept C3018795828 @default.
• W947780285 hasConcept C43617362 @default.
• W947780285 hasConcept C542903549 @default.
• W947780285 hasConcept C55493867 @default.
• W947780285 hasConcept C71924100 @default.
• W947780285 hasConcept C86803240 @default.
• W947780285 hasConcept C91523082 @default.
• W947780285 hasConcept C99454951 @default.
• W947780285 hasConceptScore W947780285C142724271 @default.
• W947780285 hasConceptScore W947780285C147483822 @default.
• W947780285 hasConceptScore W947780285C159654299 @default.
• W947780285 hasConceptScore W947780285C170493617 @default.
• W947780285 hasConceptScore W947780285C179223381 @default.
• W947780285 hasConceptScore W947780285C184112429 @default.

• next