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- W947854928 abstract "Recently, it has been reported that the luteolytic ac-tion was the main mechanism of the termination of earlypregnancy by contraceptivest. In addition, some estro-gen receptor ligands such as droloxifene have beenshown to inhibit the growth of cultured rat luteal cells.It has been known that 2-phenylindole derivatives couldcompete with estradiol for the estrogen receptor. Theseresults prompted us to design and synthesize the follow-ing six new 3-oxamoyl-2-phenylindole compounds 1a-fand test their effects on the growth of luteal cells, aimingat seeking new lead compounds possessing antifertility activities." @default.
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- W947854928 date "2001-01-01" @default.
- W947854928 modified "2023-09-26" @default.
- W947854928 title "Synthesis of Several 3-Oxamoyl-2-phenylindole Derivatives and Their Ability to Inhibit on Cultured Rat Luteal Cell Growth" @default.
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