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- W94809105 abstract "To test the association of small bile duct destructive lesions in the liver with acute graft-versus-host disease, a blind (coded) histological study was done comparing liver tissue from three groups of dogs given 1,200 R of total-body irradiation: one not given marrow infusions after irradiation, another given autologous hemopoietic grafts, and a third given marrow grafts from DLA-nonidentical unrelated donors. The dogs with unrelated grafts all developed graft-versus-host disease, and their liver histology was distinguished from that of the dogs in the other two groups of three findings: extensive small bile ductule necrosis and atypia; infiltrates of mononuclear cells around and in ductules; and individual hepatocyte necrosis scattered throughout the lobules. Thus, bile duct lesions appear to be a good marker for assessing the presence and severity of hepatic graft-versus-host disease in dogs." @default.
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- W94809105 date "1978-08-01" @default.
- W94809105 modified "2023-09-24" @default.
- W94809105 title "Histopathology of hepatic acute graft-versus-host disease in the dog. [Gamma radiation]" @default.
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