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- W948561971 abstract "目的探讨阴茎癌腹股沟淋巴结瑚-p21，p53基因蛋白的表达及临床意义。方法取收治的阴茎癌44例，随机切取腹股沟淋巴结44枚，病理证实为转移癌的18枚，炎性26枚；另选取同期腹股沟感染淋巴结20枚，正常淋巴结20枚。石蜡切片，S—P染色。检测ras—p21，p53基因蛋白的表达。结果ras—p21，p53的表达在阴茎癌腹股沟淋巴结组与对照组（正常淋巴结组、非瘤炎性淋巴结组）相比显著增高（P〈0．05）。腹股沟淋巴结癌转移阳性组较阴性组ras—p21，p53的表达显著增高（P〈0．05）。结论在淋巴结病理检查的同时行p21蛋白和053蛋白检测可提高阴茎癌转移诊断率。ras—p21蛋白和p53基因蛋白检测可以作为肿瘤是否转移和预后效果判定的客观指标。可做为阴茎癌是否行腹股沟淋巴结清除手术的判断指标。" @default.
- W948561971 created "2016-06-24" @default.
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- W948561971 date "2009-01-01" @default.
- W948561971 modified "2023-09-24" @default.
- W948561971 title "Ras—p21，p53在阴茎癌腹股沟淋巴结中的表达及临床意义" @default.
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