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- W948971064 abstract "目的研究Epstein-Barrvirus（EBV）感染的人胃上皮细胞系GE-1c-mye基因表达状况，探讨c-mye基因在EBV相关胃癌发生中的作用。方法采用携带新霉素抗性（NEO^r）基因的重组EBV产生细胞系Akata1061以密切接触法感染人胃上皮细胞系GES-1，经有限稀释法克隆和G418筛选获得感染和转染细胞克隆，用pcDNA3空载体质粒转染的人胃上皮细胞系GES-1细胞作对照，采用免疫细胞化学染色（ICC）法测定EBNAl和c-myc蛋白以鉴定EBV感染细胞克隆及c-mye基因的表达。结果EBV感染的细胞克隆经Icc法检测EBNAI阳性，c-mye蛋白阳性；对照细胞均为阴性。结论EBV感染可使人胃上皮细胞c-mye蛋白表达增高，EBV对人胃上皮细胞的转化作用可能与c-mye基因的过度表达有关。" @default.
- W948971064 created "2016-06-24" @default.
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- W948971064 date "2008-01-01" @default.
- W948971064 modified "2023-10-16" @default.
- W948971064 title "EBV感染人胃上皮细胞GES-1中c-myc基因的表达" @default.
- W948971064 hasPublicationYear "2008" @default.
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