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- W949444989 abstract "Objective To explore the capability of diffusion weighed imaging (DWI) in differentiating malignant cervical lymph nodes from benign ones in nasopharyngeal carcinoma (NPC) patients, and to assess the appropriate b value in 3.0T MR DWI. Methods Conventional MR and DWI scan were performed in 50 patients with histopathologically proven NPC and 20 healthy volunteers with GE 3.0T MR scanner, and neurovascular array 8 channels head and neck unite coil. DWI was performed with single shot spin-echo echo-planar imaging (SE-EPI) sequence at 4 different b values (600, 800, 1000, 1200 s/mm^2). The apparent diffusion coefficient (ADC) values between metastatic lymph nodes of NPC patients and benign nodes of volunteers were compared. Results The mean ADC value (×10^(-3) mm^2/s) of metastatic cervical lymph nodes of NPC at different b value (600, 800, 1000, 1200 s/mm^2) was 0.808±0.112, 0.769±0.098, 0.732±0.095 and 0.696±0.083, respectively; the mean ADC value (×10^(-3) mm^2/s) of lymph nodes of volunteers was 0.993±0.172, 0.967±0.165, 0.903±0.157 and 0.855±0.122, respectively (P＜0.05). When b value was 800 s/mm^2, and ROC cut-off point was 0.873×10^(-3) mm^2/s, the diagnostic sensitivity, specificity and accuracy was 88.41%, 69.43%, and 75.22%, respectively. Both the satisfying images and the accurate measurement were acquired. Conclusion As a rapid and sensitive new MR technique, DWI can offer help in discriminating benign and malignant cervical lymph nodes in NPC patients." @default.
- W949444989 created "2016-06-24" @default.
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- W949444989 date "2010-03-20" @default.
- W949444989 modified "2023-09-27" @default.
- W949444989 title "3.0T MR扩散加权成像鉴别鼻咽癌患者颈部转移淋巴结" @default.
- W949444989 hasPublicationYear "2010" @default.
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