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- W9497002 abstract "There are 5 different early genes of T3 and T7 that are transcribed by the host RNA polymerase. It has been found that in starved host cells T3, in contrast to T7 and SAMase-negative T3 mutants, cannot grow lytically but enters in a quasi-lysogenic state. T3 has a higher potency to grow and to damage the infected cell than T7 and the SAMase-negative derivatives of T3 in cells carrying the DNA modification and restriction system of prophage P1. The homologous and heterologous superinfection exclusion of T3 and T7 is probably a quantitative effect on gene expression. In cells carrying the DNA modification and restriction system of prophage P1, T3 has a higher potency to grow and to damage the infected cell than T7 and the SAMase-negative derivatives of T3. Phage T3 prevents the binding of the P1 restriction endonucleases to its genome by cleavage of S-adenosylmethionine, which is the cofactor for allosteric activation and DNA binding of the restriction enzyme." @default.
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- W9497002 date "1979-01-01" @default.
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- W9497002 title "MOLECULAR BIOLOGY OF BACTERIOPHAGES T3 AND T7: ROLE OF EARLY PHAGE GENES FOR VIRUS-HOST INTERACTIONS" @default.
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- W9497002 doi "https://doi.org/10.1016/b978-0-08-023175-4.50037-1" @default.
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