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- W950589500 abstract "Adenosine is a nucleoside which consists of the purine base adenine linked to ribose (Fig. 1). It is produced by two main enzymatic reactions involving dephosphorylation of 5′-nucleotidase (EC 3.1.5.5) and alkaline phosphatase (EC 3.1.3.1) as well as hydrolysis of S-adenosyl-l-homocysteine (SAH) by SAH-hydrolase (3.3.1.1). Adenosine may be formed intracellularly, as a result of a breakdown of cytosolic adenosine 5′-triphosphate (ATP), or extracellularly from ATP. In nerve tissue, an increase in nerve firing releases both adenosine and ATP, which is then extracellularly degraded to adenosine (Stone et al. 1990)." @default.
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- W950589500 date "1995-01-01" @default.
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- W950589500 title "Pharmacology of the Adenosine System" @default.
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