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- W950974741 abstract "This chapter examines the case of a man diagnosed with generalized tonic–clonic status epilepticus with myoclonic seizures secondary to an unidentified postinfectious etiology. One week before admission, a healthy 30-year-old man developed flu-like symptoms. Four days later, he had three generalized tonic–clonic seizures, which began with focal left facial twitching. He was initially treated with phenytoin and phenobarbital, but his seizures failed to respond despite a phenytoin level of 20 μg/ml and phenobarbital level of 45 μg/ml. Generalized tonic–clonic seizures were successfully terminated with phenytoin 300 mg intravenously every 6 h, valproate 750 mg intravenously every 6 h, and phenobarbital 90 mg intravenously every 8 h. When the pentobarbital was tapered, generalized tonic–clonic and myoclonic seizures returned, and these correlated with generalized polyspike-wave formations on the EEG. The EEG revealed generalized polyspike–wave activity during the myoclonic seizures. Because of some breakthrough myoclonic jerking of the face, 5-hydroxytryptophan and carbidopa were initiated. The patient was transferred back to his local community hospital 2 weeks later on 5-hydroxy-l-tryptophan 200 mg every 8 h, phenobarbital 90 mg every 6 h, and lamotrigine 100 mg every 6 h. He was eventually transferred to a rehabilitation hospital and no further seizures were reported." @default.
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- W950974741 date "2008-01-01" @default.
- W950974741 modified "2023-09-23" @default.
- W950974741 title "Status Epilepticus Responsive to Intravenous Immunoglobulin" @default.
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- W950974741 doi "https://doi.org/10.1016/b978-0-12-374005-2.00086-7" @default.
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