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- W951375036 abstract "目的进一步探讨慢性特发性血小板减少性紫癜（CITP）的发病机制。方法选择25例CITP患者（CITP组）及25例健康体检者（正常对照组），采用ELISA法检测外周血Th细胞因子IFN-γ、IL-10表达；采用RT—PCR检测外周血淋巴细胞中转录因子T-bet、GATA-3mRNA表达。结果与正常对照组相比，CITP组IFN—γ表达显著升高、IL-10表达显著降低（P〈0．01），T—betmRNA表达明显升高、GATA-3mRNA表达明显下降（P〈0．05）。结论T-bet、GATA-3表达异常在CITP发生、发展过程中发挥重要作用，可能机制为增强TM细胞功能、抑制Th2细胞功能。" @default.
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- W951375036 date "2009-01-01" @default.
- W951375036 modified "2023-09-24" @default.
- W951375036 title "T-bet、GATA-3在慢性特发性血小板减少性紫癜患者外周血中的表达及意义" @default.
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