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- W952441621 abstract "OBJECTIVE: To investigate the significance of β-catenin and MMP-7 expressions and their relations in gastric stump cancer. METHODS: β-catenin and MMP-7 were examined with the immunohistochemical SP body staining method in 32 cases of human gastric stump cancer. RESULTS: Immunohistoch emical analysis demonstrated β-catenin protein expression in 59.4% (19/32) of the gastric stump cancer and in 12.5% (4/32) of gastric stump mucosa (P=0.044), while β-catenin expression was associated with the macroscopic types, depth and size of tumors, invasive depth and growth pattern; the immunohistochemical analysis also clenostrated MMP-7 protein expression in 56.3% (18/32) of the gastric stump cancer and in 0% of gastric stump mucosa (P=0.000), while MMP-7 expression was associated with the carcinoma invasive depth, growth pattern and lymph node metastasis. The β-catenin expression was in positive correlation with the expression of MMP-7, r=0.55, P＜0.05. CONCLUSION: β-catenin and MMP-7 are associated with the developing, invasion and metastasis." @default.
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- W952441621 date "2008-04-14" @default.
- W952441621 modified "2023-09-27" @default.
- W952441621 title "残胃癌组织中β-catenin与MMP-7表达及其临床意义的研究" @default.
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