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- W953349002 abstract "To study neuronal changes that store associative memory, Pavlovian conditioning was demonstrated in a snail preparation where it was possible to precisely trace the flow of information through well-defined neuronal networks that mediate the learning. This animal can be taught to associate a light stimulus with vestibular stimulation. The excitable state in identified photoreceptors of the eye is elevated following conditioning due to persistent changes in the molecular regulation of specific potassium currents for 14 days or longer. In a second system, rabbits are conditioned to associate an auditory tone with a puff of air to the surface of the eye causing the nictitating membrane of the eye to extend on subsequent days in response to the tone alone. Memory-specific changes in ion-channel properties and their molecular basis, similar to those observed in Hermissenda, have been measured in the CA1 pyramidal cells of the rabbit hippocampus. The parallels between mechanisms of memory storage in these and other model preparations suggest conserved molecular mechanisms of memory storage." @default.
- W953349002 created "2016-06-24" @default.
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- W953349002 date "1991-01-01" @default.
- W953349002 modified "2023-09-26" @default.
- W953349002 title "Chapter 15: Activation of protein kinase C phosphorylation pathways: a role for storage of associative memory" @default.
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- W953349002 doi "https://doi.org/10.1016/s0079-6123(08)61725-2" @default.
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