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- W956284789 abstract "目的探讨甲状腺乳头状癌中caveolin-1(cav-1)与pERK1/2的表达及其意义。方法采用免疫组织化学法,检测40例甲状腺乳头状癌、11例甲状腺腺瘤及10例癌旁正常甲状腺组织中cav-1和pERK1/2的表达,并分析表达情况与临床病理参数之间的关系。结果cav-1在甲状腺腺瘤和癌旁甲状腺组织中为低表达或无表达,而在甲状腺乳头状癌中呈高表达(阳性率为60%),且与肿瘤的包膜浸润和淋巴结转移相关。pERK1/2在甲状腺乳头状癌、甲状腺腺瘤和癌旁甲状腺组织中均见表达,三者差异无统计学意义。cav-1和pERK1/2两者之间的表达无相关性。结论car-1高表达可能参与调控甲状腺乳头状癌的进展和转移,可作为预后不良的指标。" @default.
- W956284789 created "2016-06-24" @default.
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- W956284789 date "2009-01-01" @default.
- W956284789 modified "2023-09-23" @default.
- W956284789 title "caveolin-1和pER1/2在甲状腺乳头状癌中的表达及意义" @default.
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