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- W956837075 abstract "The chapter discusses the scattering studies of ribosomes and ribosomal components. Scattering methods are suitable to analyze the structural dimensions between those of the electron microscope and X-ray crystal diffraction. The gap in the structural analysis of larger cell organelles (nucleus, mitochondria, plastids), by electron microscopy and of biomacromolecules, (such as proteins or nucleic acids), by X-ray diffraction is closed increasingly by scattering methods such as light scattering (LS), small-angle X-ray scattering (SAXS), wide-angle X-ray scattering (WAXS), and small-angle neutron scattering (SANS). This chapter discusses some theoretical background of the methods, the strategy for computation and interpretation of data, and the progress achieved in the last few years regarding the structure of ribosomal components—RNA and proteins—and ribosomal particles. Most of the studies by far have been performed with ribosomal particles and their constituents from Escherichia coli and only few data are available at present on eukaryotic ribosomes. If the scattering experiment is performed in a way that both the scattering curve of the subunits and that of the associate is measured separately, or if the former is calculated, then information on the distances between the subunits and their relative positions within the associate are obtainable." @default.
- W956837075 created "2016-06-24" @default.
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- W956837075 date "1979-01-01" @default.
- W956837075 modified "2023-09-23" @default.
- W956837075 title "[53] Scattering studies of ribosomes and ribosomal components" @default.
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- W956837075 doi "https://doi.org/10.1016/0076-6879(79)59122-8" @default.
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