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Matches in SemOpenAlex for { <https://semopenalex.org/work/W958356728> ?p ?o ?g. }

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• W958356728 abstract "A series of novel STAT3 inhibitors consisting of Michael acceptor has been identified through assays of the focused in-house library. In addition, their mode of action and structural feature responsible for the STAT3 inhibition were investigated. In particular, analog 6 revealed promising STAT3 inhibitory activity in HeLa cell lines. The analog also exhibited selective inhibition of STAT3 phosphorylation without affecting STAT1 phosphorylation and cytostatic effect in human breast epithelial cells (MCF10A-ras), which supports cancer cell-specific inhibitory properties." @default.
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• W958356728 date "2015-11-01" @default.
• W958356728 modified "2023-10-16" @default.
• W958356728 title "Identification of small molecule inhibitors of the STAT3 signaling pathway: Insights into their structural features and mode of action" @default.
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• W958356728 doi "https://doi.org/10.1016/j.bmcl.2015.07.063" @default.
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