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- W958585923 abstract "The largest family of cytokine receptors is termed as hematopoietin or type I cytokine receptor family. It includes the receptors for interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), interleukin 5 (IL-5), interleukin 6 (IL-6), interleukin 7 (IL-7), interleukin 9 (IL-9), granulocyte-macrophage colony-stimulating factor (GMCSF), granulocyte colony-stimulating factor (GCSF), leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor (CNTF), erythropoietin (EPO), growth hormone, and the product of a receptor-like protooncogene (c-mpl) found after the isolation of its viral counterpart (v-mpl); no ligand has yet been identified for this molecule. Within this family, a subgroup of large cytokine receptors can be discerned that is composed of the receptors for GCSF , LIF , and oncostatin M. The oncostatin M receptor polypeptide, called gpl30, is also the β chain of the LIF and IL-6 receptors. All of the type I receptors share a domain structure in common, consisting of approximately 130 residues in the extracellular ligand-binding region, which is repeated two or more times." @default.
- W958585923 created "2016-06-24" @default.
- W958585923 creator A5009580916 @default.
- W958585923 date "1993-01-01" @default.
- W958585923 modified "2023-09-26" @default.
- W958585923 title "Pharmacological, Biochemical, and Molecular Biological Studies on Cytokine Receptors" @default.
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- W958585923 doi "https://doi.org/10.1016/b978-0-12-185281-8.50007-7" @default.
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