Matches in SemOpenAlex for { <https://semopenalex.org/work/W96004614> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W96004614 endingPage "6" @default.
- W96004614 startingPage "1123" @default.
- W96004614 abstract "We have reviewed 28 esophageal biopsies from 28 patients with the acquired immune deficiency syndrome (AIDS), over a 1-yr period. Indications for esophageal biopsy were dysphagia persisting after antifungal therapy and/or radiologic evidence of esophageal ulcer. We compared the frequency of detecting cytomegalovirus (CMV) infection on hematoxylin and eosin (H&E) stain with immunoperoxidase staining for CMV antigens. Five biopsies were positive for CMV by H&E stain and immunoperoxidase. Infected cells could often be identified in the granulation tissue and, in one severe case, in stromal papillae of the intact mucosa. Squamous cells were never positive. Thirteen biopsies consisted only of squamous epithelium, and all of these were negative by both techniques. Among the remaining 10 cases, no CMV inclusions were identified by H&E. Three of these biopsies displayed staining for viral antigens. In all cases positive by immunoperoxidase, numerous cells positive for viral antigens did not display any of the CMV-specific morphologic diagnostic criteria. Other coexisting diagnoses included candidiasis, Kaposi's sarcoma, and malignant lymphoma. We conclude 1) CMV infection of the esophagus is common in AIDS patients with esophageal ulcer or esophagitis resistant to antifungal therapy; 2) multiple infections or neoplasms may coexist; 3) since CMV apparently does not infect squamous epithelium and only rarely endothelium in stromal papillae, deep biopsies are necessary for diagnosis; and 4) immunoperoxidase staining is required for maximum diagnostic yield." @default.
- W96004614 created "2016-06-24" @default.
- W96004614 creator A5015007085 @default.
- W96004614 creator A5024836953 @default.
- W96004614 creator A5056032508 @default.
- W96004614 date "1991-09-01" @default.
- W96004614 modified "2023-09-23" @default.
- W96004614 title "Cytomegalovirus esophagitis in AIDS: diagnosis by endoscopic biopsy." @default.
- W96004614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1652884" @default.
- W96004614 hasPublicationYear "1991" @default.
- W96004614 type Work @default.
- W96004614 sameAs 96004614 @default.
- W96004614 citedByCount "8" @default.
- W96004614 countsByYear W960046142014 @default.
- W96004614 crossrefType "journal-article" @default.
- W96004614 hasAuthorship W96004614A5015007085 @default.
- W96004614 hasAuthorship W96004614A5024836953 @default.
- W96004614 hasAuthorship W96004614A5056032508 @default.
- W96004614 hasConcept C125473707 @default.
- W96004614 hasConcept C126322002 @default.
- W96004614 hasConcept C128102431 @default.
- W96004614 hasConcept C142724271 @default.
- W96004614 hasConcept C159654299 @default.
- W96004614 hasConcept C203014093 @default.
- W96004614 hasConcept C2522874641 @default.
- W96004614 hasConcept C2775934546 @default.
- W96004614 hasConcept C2776409557 @default.
- W96004614 hasConcept C2777732132 @default.
- W96004614 hasConcept C2777819096 @default.
- W96004614 hasConcept C2779134260 @default.
- W96004614 hasConcept C2779920096 @default.
- W96004614 hasConcept C2780727368 @default.
- W96004614 hasConcept C2781005205 @default.
- W96004614 hasConcept C43270747 @default.
- W96004614 hasConcept C542903549 @default.
- W96004614 hasConcept C71924100 @default.
- W96004614 hasConcept C74864618 @default.
- W96004614 hasConceptScore W96004614C125473707 @default.
- W96004614 hasConceptScore W96004614C126322002 @default.
- W96004614 hasConceptScore W96004614C128102431 @default.
- W96004614 hasConceptScore W96004614C142724271 @default.
- W96004614 hasConceptScore W96004614C159654299 @default.
- W96004614 hasConceptScore W96004614C203014093 @default.
- W96004614 hasConceptScore W96004614C2522874641 @default.
- W96004614 hasConceptScore W96004614C2775934546 @default.
- W96004614 hasConceptScore W96004614C2776409557 @default.
- W96004614 hasConceptScore W96004614C2777732132 @default.
- W96004614 hasConceptScore W96004614C2777819096 @default.
- W96004614 hasConceptScore W96004614C2779134260 @default.
- W96004614 hasConceptScore W96004614C2779920096 @default.
- W96004614 hasConceptScore W96004614C2780727368 @default.
- W96004614 hasConceptScore W96004614C2781005205 @default.
- W96004614 hasConceptScore W96004614C43270747 @default.
- W96004614 hasConceptScore W96004614C542903549 @default.
- W96004614 hasConceptScore W96004614C71924100 @default.
- W96004614 hasConceptScore W96004614C74864618 @default.
- W96004614 hasIssue "9" @default.
- W96004614 hasLocation W960046141 @default.
- W96004614 hasOpenAccess W96004614 @default.
- W96004614 hasPrimaryLocation W960046141 @default.
- W96004614 hasRelatedWork W136156342 @default.
- W96004614 hasRelatedWork W1969774428 @default.
- W96004614 hasRelatedWork W1970595985 @default.
- W96004614 hasRelatedWork W1998285885 @default.
- W96004614 hasRelatedWork W2015408932 @default.
- W96004614 hasRelatedWork W2034044130 @default.
- W96004614 hasRelatedWork W2065636067 @default.
- W96004614 hasRelatedWork W2068004077 @default.
- W96004614 hasRelatedWork W2355718751 @default.
- W96004614 hasRelatedWork W96004614 @default.
- W96004614 hasVolume "86" @default.
- W96004614 isParatext "false" @default.
- W96004614 isRetracted "false" @default.
- W96004614 magId "96004614" @default.
- W96004614 workType "article" @default.