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- W96020905 abstract "1-(m-Methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal) in oral doses of 150 mg/kg caused no essential changes in the EEG pattern in man. Only the alpha-rhythm of the occipital leads was more synchronized and the amplitude somewhat higher. beta-Waves increased slightly, but the delta-waves were not significantly changed. Tramadol induced no measurable alterations in the electronystagmographic recordings of quick voluntary eye movements or follow-up to-and-fro eye movements. In the optokinetic and postrotatory nystagmus, however, there was a moderate decrease in the total amplitude and maximal angular velocity of the slow nystagmic stage. The results of EEG and electronystagmographic investigations indicate that tramadol has a moderate relaxant (central depressant) effect." @default.
- W96020905 created "2016-06-24" @default.
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- W96020905 date "1978-01-01" @default.
- W96020905 modified "2023-09-23" @default.
- W96020905 title "[The effect of tramadol on the EEG and the electronystagmogram (author's transl)]." @default.
- W96020905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/580216" @default.
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