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- W960714497 abstract "目的探讨高级别和低级别星形细胞痈MRI DWI、肿瘤细胞密度与缺氧诱导因子-1α（HIF-1α）表达水甲的相关性。资料与方法对术后病理确诊的33例星形细胞痈患者术前行MRI DWI榆查，许计算肿瘤实质部分的ADC值；用Scion Image4．0．3．2软件计算肿痫细胞密度；采用免疫组化检测HIF-1α的表达情况。结果低级别星形细胞瘤的平均ADC值高于高级别星形细胞瘤，差异有统计学意义（t=7．300，P〈0．001）。高级别星形细胞瘤平均细胞密度值叫显大于低级别星形细胞痛，差异有统计学意义（t=-3．845，P〈0．01）。低级别和高级别星形细胞瘤中均有HIF-1α表达，其表达强度分别为（20．08±10．01）％、（47．91±19．03）％。肿瘤ADC值与H1F-1α标记指数、肿痛细胞密度值呈显著负相关（r=-0．756、-O.617，P〈0．001），HIF-1α和肿瘤细胞密度值呈显著正相关（r=0．622，P〈0．001）。结论ADC值有助于初步判定星形细胞瘤的性质，对低级别和高级别星形细胞瘤有一定的鉴别人价值。HIF-1α在星形细胞痛中的作用应扩大样本量进一步深入研宄。" @default.
- W960714497 created "2016-06-24" @default.
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- W960714497 date "2013-01-01" @default.
- W960714497 modified "2023-09-28" @default.
- W960714497 title "星形细胞瘤MRI扩散加权成像、肿瘤细胞密度与缺氧诱导因子-1α表达水平的相关性" @default.
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