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- W960976511 abstract "This chapter discusses the structure, organization, and function of the kinetochore and the problems that remain that are mostly of a structural, physicochemical, and cytogenetic nature.At the structural level organisms with particular kinetochore behavior need to be investigated, such as plants with diffuse kinetochores (Luzula) or with rings of chromosomes (Oenothera) and the pattern of the chromosome arms need to be analyzed. In the study of chromosome movements during the past several years, the use of fixed and stained material has been of value in suggesting the main trends of research, but it has contributed little to the insights into the essential mechanism involved. A problem concerns the relation of the kinetochore to the formation of the chromosome pattern. The structural analysis is most valuable in disclosing the process itself, revealing its variation, and suggesting the mechanisms responsible. But the demonstration of the interactions involved can only come from the experimental analysis made with the help of cytogenetic methods using mainly structural rearrangements. These are some of the main problems, which at present may be visualized concerning the future development of research on the kinetochore." @default.
- W960976511 created "2016-06-24" @default.
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- W960976511 date "1958-01-01" @default.
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- W960976511 title "Recent Advances in the Study of the Kinetochore" @default.
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- W960976511 doi "https://doi.org/10.1016/s0074-7696(08)62686-8" @default.
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