Matches in SemOpenAlex for { <https://semopenalex.org/work/W96122261> ?p ?o ?g. }
- W96122261 endingPage "159" @default.
- W96122261 startingPage "143" @default.
- W96122261 abstract "It has been known for many years that changes in the level of systemic vascular resistance (SVR) will influence the magnitude of regurgitant flow across an incompetent aortic valve. As depicted in Figure 8–1, factors that increase tone in peripheral arterial resistance vessels will enhance regurgitant flow, while those that reduce tone will diminish it. However, it was not until the mid-1970s that this knowledge was utilized in devising new modalities of therapy for patients with aortic insufficiency. During this period, physicians were becoming increasingly aware of the adverse affects of high levels of SVR in patients with congestive heart failure (CHF), and there was ample documentation in the medical literature that vasodilator drugs could substantially improve cardiac performance in this setting [1–6]. The benefits of vasodilator drugs in mitral insufficiency, a lesion that is analagous to aortic insufficiency in that the amount of regurgitant flow is sensitive to changes in the level of SVR, had also been demonstrated [7–11]. Initially, there was some concern that vasodilators might not be effective in patients with aortic insufficiency, since many peripheral manifestations of this disease (e.g., wide arterial pulse pressure with low diastolic pressure, Quincke’s pulse, etc.) suggest that tone in arterial resistance vessels is already low. However, subsequent reports demonstrated that vasodilators were indeed capable of improving cardiac performance in patients with aortic insufficiency [12–15].KeywordsSystemic Vascular ResistanceAortic RegurgitationAortic InsufficiencyVasodilator TherapyPulmonary Artery Wedge PressureThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W96122261 created "2016-06-24" @default.
- W96122261 creator A5064906147 @default.
- W96122261 date "1988-01-01" @default.
- W96122261 modified "2023-09-28" @default.
- W96122261 title "Vasodilator Therapy of Chronic Aortic Regurgitation" @default.
- W96122261 cites W1965546943 @default.
- W96122261 cites W1967643219 @default.
- W96122261 cites W1967683301 @default.
- W96122261 cites W1969049964 @default.
- W96122261 cites W1976090161 @default.
- W96122261 cites W1976369182 @default.
- W96122261 cites W1988124306 @default.
- W96122261 cites W1996316222 @default.
- W96122261 cites W1997486245 @default.
- W96122261 cites W1997695618 @default.
- W96122261 cites W2003839951 @default.
- W96122261 cites W2007979523 @default.
- W96122261 cites W2011874553 @default.
- W96122261 cites W2014882876 @default.
- W96122261 cites W2016074336 @default.
- W96122261 cites W2016220105 @default.
- W96122261 cites W2016761855 @default.
- W96122261 cites W2020256998 @default.
- W96122261 cites W2021235511 @default.
- W96122261 cites W2027555503 @default.
- W96122261 cites W2028537624 @default.
- W96122261 cites W2029789299 @default.
- W96122261 cites W2032278417 @default.
- W96122261 cites W2043107614 @default.
- W96122261 cites W2053160889 @default.
- W96122261 cites W2053625842 @default.
- W96122261 cites W2054467507 @default.
- W96122261 cites W2061362431 @default.
- W96122261 cites W2061869466 @default.
- W96122261 cites W2063043755 @default.
- W96122261 cites W2065827711 @default.
- W96122261 cites W2079045333 @default.
- W96122261 cites W2079256064 @default.
- W96122261 cites W2085413813 @default.
- W96122261 cites W2086505681 @default.
- W96122261 cites W2087476607 @default.
- W96122261 cites W2088838158 @default.
- W96122261 cites W2092701993 @default.
- W96122261 cites W2095049778 @default.
- W96122261 cites W2104475665 @default.
- W96122261 cites W2112232492 @default.
- W96122261 cites W2115526864 @default.
- W96122261 cites W2140997178 @default.
- W96122261 cites W2146311859 @default.
- W96122261 cites W2161497583 @default.
- W96122261 doi "https://doi.org/10.1007/978-1-4613-1729-6_8" @default.
- W96122261 hasPublicationYear "1988" @default.
- W96122261 type Work @default.
- W96122261 sameAs 96122261 @default.
- W96122261 citedByCount "0" @default.
- W96122261 crossrefType "book-chapter" @default.
- W96122261 hasAuthorship W96122261A5064906147 @default.
- W96122261 hasConcept C120770815 @default.
- W96122261 hasConcept C126322002 @default.
- W96122261 hasConcept C164705383 @default.
- W96122261 hasConcept C2778198053 @default.
- W96122261 hasConcept C2780168065 @default.
- W96122261 hasConcept C58245268 @default.
- W96122261 hasConcept C71924100 @default.
- W96122261 hasConcept C84393581 @default.
- W96122261 hasConceptScore W96122261C120770815 @default.
- W96122261 hasConceptScore W96122261C126322002 @default.
- W96122261 hasConceptScore W96122261C164705383 @default.
- W96122261 hasConceptScore W96122261C2778198053 @default.
- W96122261 hasConceptScore W96122261C2780168065 @default.
- W96122261 hasConceptScore W96122261C58245268 @default.
- W96122261 hasConceptScore W96122261C71924100 @default.
- W96122261 hasConceptScore W96122261C84393581 @default.
- W96122261 hasLocation W961222611 @default.
- W96122261 hasOpenAccess W96122261 @default.
- W96122261 hasPrimaryLocation W961222611 @default.
- W96122261 hasRelatedWork W1588254627 @default.
- W96122261 hasRelatedWork W1964711790 @default.
- W96122261 hasRelatedWork W1965612258 @default.
- W96122261 hasRelatedWork W197724399 @default.
- W96122261 hasRelatedWork W1982225104 @default.
- W96122261 hasRelatedWork W1986877006 @default.
- W96122261 hasRelatedWork W2000347440 @default.
- W96122261 hasRelatedWork W2013783414 @default.
- W96122261 hasRelatedWork W2018288720 @default.
- W96122261 hasRelatedWork W2044727006 @default.
- W96122261 hasRelatedWork W205183055 @default.
- W96122261 hasRelatedWork W2065933006 @default.
- W96122261 hasRelatedWork W2095310250 @default.
- W96122261 hasRelatedWork W2101225010 @default.
- W96122261 hasRelatedWork W2115682628 @default.
- W96122261 hasRelatedWork W2164541719 @default.
- W96122261 hasRelatedWork W2314942000 @default.
- W96122261 hasRelatedWork W2409983614 @default.
- W96122261 hasRelatedWork W27158316 @default.
- W96122261 hasRelatedWork W2727321098 @default.
- W96122261 isParatext "false" @default.