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- W961542009 abstract "Publisher Summary This chapter discusses the involvement of nucleic acids in bacterial injury. The involvement of ribonucleic acid (RNA) in sublethal stress of bacteria has been widely studied. It is noted that the degradation of ribosomes and ribosomal RNA (rRNA) was a generally observed lesion following sublethal stress. The rRNA comprises approximately 63% of the weight of a ribosome. In mature ribosomes, rRNA causes ribosomal proteins to maintain the proper configuration that permits the ribosome to perform its function during protein biosynthesis. The involvement of RNA in injury was first recognized when investigators found that bacterial cells lost 260 nm-absorbing materials when the cells were submitted to temperatures slightly above their maximum growth temperature. The rRNA and ribosome degradation occur during heat-injury. The type and extent of degradation of 16 S and 23 S rRNA, and 50 S and 30 S ribosome subunits is not the same, but the 16 S rRNA and 30 S subunit appear to be affected more readily than 23 S rRNA and 50 S subunit. There appears to be synthesis of both 50 S and 30 S ribosomes and 23 S and 16 S rRNA during recovery." @default.
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- W961542009 date "1978-01-01" @default.
- W961542009 modified "2023-10-18" @default.
- W961542009 title "The Involvement of Nucleic Acids in Bacterial Injury" @default.
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- W961542009 doi "https://doi.org/10.1016/s0065-2164(08)70073-x" @default.
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