FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W962646766> ?p ?o ?g. }

• W962646766 endingPage "1269" @default.
• W962646766 startingPage "1263" @default.
• W962646766 abstract "RNA extracted from a free polysome fraction from rat liver was used to direct translation in nuclease-treated rabbit reticulocyte lysates, and the [35S]methionine-labelled, in vitro-synthesized, cytochrome b5 reductase was isolated with specific antibodies. Analysis by SDS-polyacrylamide gel electrophoresis, non-equilibrium pH gradient electrophoresis and one-dimensional peptide mapping failed to reveal any difference between the in vitro-synthesized reductase and the enzyme endogenous to rat liver microsomes. To study the integration of the in vitro-synthesized reductase into membranes, carboxypeptidase Y was used as a proteolytic probe. The reductase endogenous to rat liver microsomes was resistant to attack by carboxypeptidase Y, but was degraded to a smaller form when the microsomes were solubilized by detergent. Likewise, the enzyme synthesized in vitro was attacked by carboxypeptidase Y, but became largely resistant after post-translational incubation with dog pancreatic microsomes, indicating that an integration into membranes similar to the physiological one had occurred. It is concluded that cytochrome b5 reductase is probably not synthesized as a precursor and inserts post-translationally into the membrane. The results are discussed in relation to the particular subcellular distribution of the reductase and to the possible topology in the lipid bilayer of its C-terminal non-polar membrane-binding segment." @default.
• W962646766 created "2016-06-24" @default.
• W962646766 creator A5009959598 @default.
• W962646766 creator A5063264447 @default.
• W962646766 date "1983-08-01" @default.
• W962646766 modified "2023-10-02" @default.
• W962646766 title "In vitro synthesis and post-translational insertion into microsomes of the integral membrane protein, NADH-cytochrome b5 oxidoreductase." @default.
• W962646766 cites W1486318341 @default.
• W962646766 cites W1502053909 @default.
• W962646766 cites W1504179388 @default.
• W962646766 cites W1511440139 @default.
• W962646766 cites W1532043255 @default.
• W962646766 cites W1555829980 @default.
• W962646766 cites W1581322455 @default.
• W962646766 cites W1602964350 @default.
• W962646766 cites W1606423922 @default.
• W962646766 cites W1775749144 @default.
• W962646766 cites W1965092010 @default.
• W962646766 cites W1968029145 @default.
• W962646766 cites W1970081885 @default.
• W962646766 cites W1970403529 @default.
• W962646766 cites W1996759199 @default.
• W962646766 cites W2006951063 @default.
• W962646766 cites W2018289835 @default.
• W962646766 cites W2025826147 @default.
• W962646766 cites W2027407556 @default.
• W962646766 cites W2030685467 @default.
• W962646766 cites W2033317965 @default.
• W962646766 cites W2040812386 @default.
• W962646766 cites W2043469241 @default.
• W962646766 cites W2051250838 @default.
• W962646766 cites W2066160869 @default.
• W962646766 cites W2076424193 @default.
• W962646766 cites W2076739096 @default.
• W962646766 cites W2078918456 @default.
• W962646766 cites W2083453910 @default.
• W962646766 cites W2088676976 @default.
• W962646766 cites W2089433125 @default.
• W962646766 cites W2091847322 @default.
• W962646766 cites W2093347267 @default.
• W962646766 cites W2101108802 @default.
• W962646766 cites W2146923243 @default.
• W962646766 cites W2162755916 @default.
• W962646766 cites W2164358316 @default.
• W962646766 cites W2168526937 @default.
• W962646766 cites W2171903383 @default.
• W962646766 cites W3209951468 @default.
• W962646766 cites W383663030 @default.
• W962646766 cites W69995815 @default.
• W962646766 doi "https://doi.org/10.1002/j.1460-2075.1983.tb01579.x" @default.
• W962646766 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/555270" @default.
• W962646766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10872318" @default.
• W962646766 hasPublicationYear "1983" @default.
• W962646766 type Work @default.
• W962646766 sameAs 962646766 @default.
• W962646766 citedByCount "17" @default.
• W962646766 countsByYear W9626467662017 @default.
• W962646766 crossrefType "journal-article" @default.
• W962646766 hasAuthorship W962646766A5009959598 @default.
• W962646766 hasAuthorship W962646766A5063264447 @default.
• W962646766 hasBestOaLocation W9626467661 @default.
• W962646766 hasConcept C104317684 @default.
• W962646766 hasConcept C108477463 @default.
• W962646766 hasConcept C116084860 @default.
• W962646766 hasConcept C134651460 @default.
• W962646766 hasConcept C153911025 @default.
• W962646766 hasConcept C181199279 @default.
• W962646766 hasConcept C2778403015 @default.
• W962646766 hasConcept C2779384962 @default.
• W962646766 hasConcept C55493867 @default.
• W962646766 hasConcept C67705224 @default.
• W962646766 hasConcept C86803240 @default.
• W962646766 hasConcept C87644729 @default.
• W962646766 hasConceptScore W962646766C104317684 @default.
• W962646766 hasConceptScore W962646766C108477463 @default.
• W962646766 hasConceptScore W962646766C116084860 @default.
• W962646766 hasConceptScore W962646766C134651460 @default.
• W962646766 hasConceptScore W962646766C153911025 @default.
• W962646766 hasConceptScore W962646766C181199279 @default.
• W962646766 hasConceptScore W962646766C2778403015 @default.
• W962646766 hasConceptScore W962646766C2779384962 @default.
• W962646766 hasConceptScore W962646766C55493867 @default.
• W962646766 hasConceptScore W962646766C67705224 @default.
• W962646766 hasConceptScore W962646766C86803240 @default.
• W962646766 hasConceptScore W962646766C87644729 @default.
• W962646766 hasIssue "8" @default.
• W962646766 hasLocation W9626467661 @default.
• W962646766 hasLocation W9626467662 @default.
• W962646766 hasLocation W9626467663 @default.
• W962646766 hasOpenAccess W962646766 @default.
• W962646766 hasPrimaryLocation W9626467661 @default.
• W962646766 hasRelatedWork W1514806293 @default.
• W962646766 hasRelatedWork W1833247211 @default.
• W962646766 hasRelatedWork W1864618276 @default.
• W962646766 hasRelatedWork W1964211777 @default.
• W962646766 hasRelatedWork W1992304962 @default.
• W962646766 hasRelatedWork W2010372900 @default.
• W962646766 hasRelatedWork W2016801882 @default.

• next