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- W962772090 abstract "This chapter concentrates on the Ca-sensitive K permeability mechanism of red cells. Although the functional role of this process is completely unknown in these cells, the red cell membrane represents an extremely convenient experimental model for the study of such a mechanism. Ca-induced K flux is so easy to measure and so richly responsive to all sorts of treatments that it has stimulated more extensive than analytical research. The chapter explores that as an experimental model, the red cell has clear advantages in that Ca2+ can be assessed and controlled better than in any other cell, and in that even minute selective changes in K permeability can be unambiguously determined by relatively simple methods. Furthermore, investigation of the molecular nature of the Ca-sensitive K channel is still at a very early stage. Moreover, a few attempts have been made to search for specific high affinity inhibitors with which the channels can be “labeled,” their surface density can be measured, but the results so far are not very promising." @default.
- W962772090 created "2016-06-24" @default.
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- W962772090 date "1978-01-01" @default.
- W962772090 modified "2023-10-17" @default.
- W962772090 title "Calcium Transport and the Properties of a Calcium-Activated Potassium Channel in Red Cell Membranes" @default.
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- W962772090 doi "https://doi.org/10.1016/s0070-2161(08)60836-9" @default.
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