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- W9628304 abstract "Hematopoiesis is a profound example of cell homeostasis which is regulated throughout life, whereby a hierarchy of hematopoietic progenitor cells in the bone marrow (BM) proliferate and terminally differentiate along multiple, distinct cell lineages. This includes the proliferation and differentiation of myeloid precursor cells into granulocytes and macrophages (33, 40, 42). Clearly, a variety of control mechanisms are needed to maintain steady state levels of mature blood cells, as well as to stimulate the rapid production of specific cell types as needed. To achieve this requires the participation of many factors, including positive and negative regulators of growth and differentiation, which determine survival, growth stimulation, differentiation, functional activation, and programmed cell death (apoptosis) (41, 44)." @default.
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- W9628304 date "1996-01-01" @default.
- W9628304 modified "2023-09-23" @default.
- W9628304 title "Role of c-myc in Myeloid Differentiation, Growth Arrest and Apoptosis" @default.
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- W9628304 doi "https://doi.org/10.1007/978-3-642-85232-9_3" @default.
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