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- W962860470 endingPage "52" @default.
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- W962860470 abstract "Pterinoid investigations have steadily extended knowledge of (1) transfer of C1 groups, (2) biosynthetic and functional connections between folic vitamins and other nitrogenous heterocycles—purines, thymine (or thymidine), riboflavin, vitamins Bs and BIZ, and unconjugated pterins. Ever since F. G. Hopkins looked into the pigments of butterfly wings, these unconjugated pterins (for example xanthopterin and leucopterin) have been a biosynthetic enigma. The advent of folic acid complicated matters. A solution is in sight thanks to other lines of investigation converging: (1) the eye pigments of Drosophilu—classical objects of genetics—are predominantly pterins in some mutants, (2) the flagellate Crithidia fasciculata requires certain unconjugated pterins, PGA apparently being the precursor, and (3) remarkably high concentrations of pterins, some with Crithidiu-factor activity, occur in blue-green algae and are somehow involved in photosynthesis. Evidently, certain unconjugated pterins have an essential, unknown function. This chapter attempts to collate clues to new relationships and functions of pterinoids; its point of departure is the exhaustive treatment of p-aminobenzoic acid (PABA) by Wright and Taormina, and of the folic vitamin family by Stokstad and others. Uses of microbial systems and the comparative biochemistry of pterinoids are emphasized in the chapter." @default.
- W962860470 created "2016-06-24" @default.
- W962860470 creator A5017495204 @default.
- W962860470 creator A5031803231 @default.
- W962860470 creator A5050466998 @default.
- W962860470 date "1959-01-01" @default.
- W962860470 modified "2023-09-26" @default.
- W962860470 title "Metabolism of Folic Acid and Other Pterin-Pteridine Vitamins" @default.
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