FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W96287079> ?p ?o ?g. }

• W96287079 endingPage "25" @default.
• W96287079 startingPage "315" @default.
• W96287079 abstract "After 13 years of transplant experience in our center, we analyzed the results in the overall population and in particular subgroups of heart transplant recipients. We tried to identify risk factors for both early (3 months) and late (over 3 months) mortality after heart transplantation.The data on 461 patients transplanted from November 1985-June 1998 were reviewed. To study risk factors for mortality, the results for 313 patients operated on from June 1985-June 1995 were studied and analyzed with a multivariate logistic regression and Cox's proportional hazard model. Seventy pre-, intra- and postoperative variables were considered including patient demographics, clinical status, hemodynamic parameters, donor characteristics, donor-recipient HLA mismatches, complications, and immunosuppressive protocols. We also compared results for patients transplanted from 1985-1991 (Group 1) and from 1992-1998 (Group II) to assess improvements due to changes in indications and in perioperative treatments.Overall mortality in the entire population was 20.2% (93/461). The 30-day, 3-month and late mortality rates were 8.0%, 10.2%, 11.1%, respectively. Group II mortality rates were 6.5%, 8.5% and 6.8%, respectively, despite a significant increase in Status I patients (20.6% in Group I vs 49.0% in Group II, p = 0.0001). The main causes of death were graft failure (24.7%), cardiac allograft vasculopathy (18.3%), and infection (16.1%). The mean follow-up of the 414 recipients who survived more than 3 months was 54.0 +/- 37.3 months. Actuarial survival was 87.4%, 79.2% and 68.9% at one, 5 and 10 years, respectively. The difference in the 5-year actuarial survival rates between Group I and Group II patients was statistically significant (73.5% vs 83.9%, p = 0.0135). The transpulmonary gradient, right atrial pressure and mid-high doses of donor inotropic support were identified as independent risk factors for early mortality. The number of moderate rejections at biopsy and early posttransplant infections were identified as independent risk factors for late mortality. The results of patients transplanted while on ventricular assist devices, urgent and elective patients and combined heart and kidney transplants were also reported.The overall results of our 13-year experience are very satisfying in relation to early and late mortality, with a significant favorable trend between patients transplanted in the early era (1985-1991) and those transplanted in the recent era (1992-1998). Pulmonary hypertension and elevated preoperative right filling pressure appear to indicate a significantly increased risk of early death and only marginally influence late survival, which is principally influenced by severe postoperative complications. Good results were achieved in combined heart and kidney transplantation and among patients who deteriorated during the waiting period and were supported with ventricular assist devices. The early and late outcomes for urgent (status I) and elective (status II) heart transplant patients were comparable." @default.
• W96287079 created "2016-06-24" @default.
• W96287079 creator A5010498880 @default.
• W96287079 creator A5011827781 @default.
• W96287079 creator A5016975649 @default.
• W96287079 creator A5021225362 @default.
• W96287079 creator A5032174472 @default.
• W96287079 creator A5032514014 @default.
• W96287079 creator A5033875378 @default.
• W96287079 creator A5047134412 @default.
• W96287079 creator A5054605837 @default.
• W96287079 creator A5057006507 @default.
• W96287079 creator A5062882537 @default.
• W96287079 creator A5080686515 @default.
• W96287079 creator A5084067307 @default.
• W96287079 date "1998-01-01" @default.
• W96287079 modified "2023-10-03" @default.
• W96287079 title "Heart transplantation 1985-1998: 13-years experience at Angelo De Gasperis Cardio-Thoracic Department-Milan." @default.
• W96287079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10503110" @default.
• W96287079 hasPublicationYear "1998" @default.
• W96287079 type Work @default.
• W96287079 sameAs 96287079 @default.
• W96287079 citedByCount "1" @default.
• W96287079 countsByYear W962870792015 @default.
• W96287079 crossrefType "journal-article" @default.
• W96287079 hasAuthorship W96287079A5010498880 @default.
• W96287079 hasAuthorship W96287079A5011827781 @default.
• W96287079 hasAuthorship W96287079A5016975649 @default.
• W96287079 hasAuthorship W96287079A5021225362 @default.
• W96287079 hasAuthorship W96287079A5032174472 @default.
• W96287079 hasAuthorship W96287079A5032514014 @default.
• W96287079 hasAuthorship W96287079A5033875378 @default.
• W96287079 hasAuthorship W96287079A5047134412 @default.
• W96287079 hasAuthorship W96287079A5054605837 @default.
• W96287079 hasAuthorship W96287079A5057006507 @default.
• W96287079 hasAuthorship W96287079A5062882537 @default.
• W96287079 hasAuthorship W96287079A5080686515 @default.
• W96287079 hasAuthorship W96287079A5084067307 @default.
• W96287079 hasConcept C126322002 @default.
• W96287079 hasConcept C141071460 @default.
• W96287079 hasConcept C151956035 @default.
• W96287079 hasConcept C207103383 @default.
• W96287079 hasConcept C2778849806 @default.
• W96287079 hasConcept C2908647359 @default.
• W96287079 hasConcept C2911091166 @default.
• W96287079 hasConcept C31174226 @default.
• W96287079 hasConcept C44249647 @default.
• W96287079 hasConcept C50382708 @default.
• W96287079 hasConcept C71924100 @default.
• W96287079 hasConcept C99454951 @default.
• W96287079 hasConceptScore W96287079C126322002 @default.
• W96287079 hasConceptScore W96287079C141071460 @default.
• W96287079 hasConceptScore W96287079C151956035 @default.
• W96287079 hasConceptScore W96287079C207103383 @default.
• W96287079 hasConceptScore W96287079C2778849806 @default.
• W96287079 hasConceptScore W96287079C2908647359 @default.
• W96287079 hasConceptScore W96287079C2911091166 @default.
• W96287079 hasConceptScore W96287079C31174226 @default.
• W96287079 hasConceptScore W96287079C44249647 @default.
• W96287079 hasConceptScore W96287079C50382708 @default.
• W96287079 hasConceptScore W96287079C71924100 @default.
• W96287079 hasConceptScore W96287079C99454951 @default.
• W96287079 hasLocation W962870791 @default.
• W96287079 hasOpenAccess W96287079 @default.
• W96287079 hasPrimaryLocation W962870791 @default.
• W96287079 hasRelatedWork W1964601006 @default.
• W96287079 hasRelatedWork W2047967234 @default.
• W96287079 hasRelatedWork W2061383329 @default.
• W96287079 hasRelatedWork W2102785699 @default.
• W96287079 hasRelatedWork W2155089314 @default.
• W96287079 hasRelatedWork W2373658663 @default.
• W96287079 hasRelatedWork W2386769168 @default.
• W96287079 hasRelatedWork W2604010579 @default.
• W96287079 hasRelatedWork W2755206669 @default.
• W96287079 hasRelatedWork W3203247996 @default.
• W96287079 isParatext "false" @default.
• W96287079 isRetracted "false" @default.
• W96287079 magId "96287079" @default.
• W96287079 workType "article" @default.