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- W9635609 abstract "This chapter discusses the clinical features of osteoporosis in cardiac transplant recipients as well as the mechanisms of bone loss that may occur before and after transplantation. Congestive heart failure (CHF) is not associated with a specific type of bone disease. Patients approaching cardiac transplant can experience bone insults related to drugs, such as heparin, or loop diuretics, immobility, and vitamin D deficiency. Evaluations of bone mineral density in such populations have shown that osteoporosis and osteopenia are common in patients with severe CHF. Patients with CHF may also have abnormal bone and mineral homeostasis related to both the pathophysiology and the therapy of their cardiac disease. Patients with end-stage cardiac disease have risk factors for osteoporosis, such as older age, postmenopausal status, physical inactivity, and excessive use of tobacco and alcohol. Therapy with anticoagulants, such as heparin and warfarin, could contribute to bone loss. Long-term use of heparin has been associated with bone mineral density losses and vertebral fractures. The chapter describes a treatment strategy that may benefit patients with this unique type of bone disease." @default.
- W9635609 created "2016-06-24" @default.
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- W9635609 date "2005-01-01" @default.
- W9635609 modified "2023-10-16" @default.
- W9635609 title "Bone Disease in Patients before and after Cardiac Transplantation" @default.
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- W9635609 doi "https://doi.org/10.1016/b978-012183502-6/50017-1" @default.
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