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- W963672328 abstract "This chapter describes the effect of midbrain raphe lesion on diurnal and stress-induced changes in serotonin content of discrete regions of the limbic system and adrenal function in the rat. In the normal animal, the serotonin levels in the mesencephalon, hippocampus, septum, amygdala and hypothalamus showed a diurnal rhythm having the highest level between 8 h and 16 h in the mesencephalon, septum and amygdala, and between 8 h and 12 h in the hippocampus and hypothalamus. The stress response was facilitated in the raphe-lesioned animal and return to the resting value was delayed. The hypothalamic serotonin level did not change during stress. The results suggest that the mesencephalic raphe nuclei play an important role in the maintenance of the serotonin rhythm in the brain, which is in negative correlation with the diurnal adrenal rhythm the serotonin rhythm in the brain, which is in negative correlation with the diurnal adrenal rhythm." @default.
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- W963672328 date "1975-01-01" @default.
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- W963672328 title "Mechanism of reserpine-induced changes in the pituitary-gonActal axis in rats" @default.
- W963672328 doi "https://doi.org/10.1016/s0079-6123(08)63685-7" @default.
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