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• W96585142 abstract "This chapter discusses the neuroendocrine-immune network, nociceptive stress, and the general adaptive response. Human beings are faced with protecting their body against the extremely varied and often harsh external environmental conditions. The messenger molecules of the neuroendocrine-immune network, variously termed neuroregulators, immunoregulators and hormones, are produced and secreted in normal baseline rhythms which serve to define the homoeostatic condition of the body. The integrated interactions of these three types of messenger molecules tie the neural, immune, and endocrine systems into one functional network. Alterations in the rhythmical secretion of these messenger molecules are initiated in response to potentially harmful stimuli from either outside or inside of one's bodies. These harmful or potentially harmful stimuli were called stressors. The alteration in body chemistry to such stressors defines the general adaptive response. As impending threats diminish, feedback regulatory pathways function to re-establish the normal baseline rhythms of messenger molecule secretion, thereby diminishing the general adaptive response. The protective homoeostatic activities of the neuroendocrine-immune network are responsive to two major types of sensory information, neural, and immune. The peripheral nervous system is capable of detecting changes in various forms of energy surrounding and within the body, such as mechanical, chemical, and light energy." @default.
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• W96585142 date "1995-01-01" @default.
• W96585142 modified "2023-09-27" @default.
• W96585142 title "Neuroendocrine—immune network, nociceptive stress and the general adaptive response" @default.
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• W96585142 doi "https://doi.org/10.1016/b978-0-7506-1700-0.50014-4" @default.
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