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- W966050892 abstract "目的探讨CD44v6、整合素β1（Integrinβ1 INTβ1）及基质金属蛋白酶-9（MMP-9）在宫颈癌组织中的表达、相互关系及临床意义。方法采用免疫组织化学SP方法检测CD44v6、Integrinβ1及MMP-9在正常宫颈组织、宫颈上皮内瘤变（CINⅡ-Ⅲ）和宫颈癌组织中的表达情况。所有资料应用SPSS软件10.0版分析处理,以P〈0.05作为检验标准。结果CD44v6、Integrinβ1及MMP-9在正常宫颈组织、CIN（Ⅱ-Ⅲ）和宫颈浸润癌中的阳性表达组间差异有统计学意义。CD44v6、Integrinβ1及MMP-9的阳性表达与淋巴结转移有关（P〈0.05）,与临床分期、组织分化、组织学类型无关（P〉0.05）。宫颈癌组织中CD44v6、Integrinβ1及MMP-9的表达呈正相关。结论CD44v6、Integrinβ1及MMP-9蛋白异常表达在宫颈癌侵袭和转移中起重要作用,联合检测这些指标可以预测宫颈癌组织的侵袭和转移能力。" @default.
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- W966050892 date "2009-01-01" @default.
- W966050892 modified "2023-09-24" @default.
- W966050892 title "CD44v6 Integrin β1及MMP-9在宫颈癌组织中的表达及意义" @default.
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