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- W966609124 abstract "The first such study was a case-control study performed in Arizona in December 1978 [1]. Seven school-aged children with Reye’s syndrome were compared to 16 classmates, matched for sex and suffering from an illness during the same month as the cases. The parents of patients were interviewed, exploring exposures during the time prior to the vomiting in the cases and during the entire illness in the controls. It was found that fever was more common in the cases (p=0.05) and that cases took more medications (p=0.05). In particular, of the seven cases, all took aspirin. Of the 16 controls, only 8 did. This gave an odds ratio which was indefinite (p<0.05). There was a relationship between dose of aspirin and the severity of the disease which was statistically significant. Finally, analysing only those who had suffered from fever, there still remained a relationship between aspirin and development of Reye’s syndrome (p<0.01)." @default.
- W966609124 created "2016-06-24" @default.
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- W966609124 date "1992-01-01" @default.
- W966609124 modified "2023-09-24" @default.
- W966609124 title "Aspirin and Reye’s syndrome" @default.
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- W966609124 doi "https://doi.org/10.1007/978-94-011-2982-4_29" @default.
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