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- W9666513 abstract "The race to sequence the human genome, culminating with two ground-breaking publications in 2001 (1,2),drew enormous attention to the possibility of using genetic information for diagnostic purposes, to guide therapy, for development of new therapeutics, or even for disease prevention. Despite the unquestioned importance of an organism’s genes, it is the products of gene expression, the proteins, that will manifest health or disease. Furthering our understanding of how proteins are involved in the development or manifestation of diseases will increase our knowledge about the underlying pathological processes on the cellular level. Instead of simply “observing and analyzing pathological alterations; proteomics will permit the dissection of pathological pathways (3).” It should therefore become possible to explain why subgroups of patients have a better prognosis than others or respond differently to certain therapies. This will not only influence therapies through development of new therapeutic agents, but will also improve existing diagnostics. Furthermore, this may lead to the development of both new diagnostics and therapies, individually tailored to specific proteome phenotypes." @default.
- W9666513 created "2016-06-24" @default.
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- W9666513 date "2003-01-01" @default.
- W9666513 modified "2023-10-14" @default.
- W9666513 title "Cardiac Troponins: Exploiting the Diagnostic Potential of Disease-Induced Protein Modifications" @default.
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- W9666513 doi "https://doi.org/10.1007/978-1-59259-385-9_7" @default.
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