Matches in SemOpenAlex for { <https://semopenalex.org/work/W96676145> ?p ?o ?g. }
- W96676145 abstract "To determine the factors affecting mortality in patients who developed graft-versus-host disease (GvHD) after liver transplantation (LT).We performed a review of studies of GvHD following LT published in the English literature and accessed the PubMed, Medline, EBSCO, EMBASE, and Google Scholar databases. Using relevant search phrases, 88 articles were identified. Of these, 61 articles containing most of the study parameters were considered eligible for the study. Risk factors were first examined using a univariate Kaplan-Meier model, and variables with a significant association (P < 0.05) were then subjected to multivariate analyses using a Cox proportional-hazards model.The 61 articles reported 87 patients, 58 male and 29 female, mean age, 40.4 ± 15.5 years (range: 8 mo to 74 years), who met the inclusion criteria for the present study. Deaths occurred in 59 (67.8%) patients, whereas 28 (32.2%) survived after a mean follow-up period of 280.8 ± 316.2 d (range: 27-2285 d). Among the most frequent symptoms were rash (94.2%), fever (66.6%), diarrhea (54%), and pancytopenia (54%). The average time period between LT and first symptom onset was 60.6 ± 190.1 d (range: 2-1865 d). The Kaplan-Meier analysis revealed that pancytopenia (42.8% vs. 59.3%, P = 0.03), diarrhea (39.2% vs. 61.0%, P = 0.04), age difference between the recipient and the donor (14.6 ± 3.1 years vs. 22.6 ± 2.7 years, P < 0.0001), and time from first symptom occurrence to diagnosis or treatment (13.3 ± 2.6 mo vs. 15.0 ± 2.3 mo, P < 0.0001) were significant factors affecting mortality, whereas age, sex, presence of rash and fever, use of immunosuppressive agents, acute rejection before GvHD, etiological causes, time of onset, and donor type were not associated with mortality risk. The Cox proportional-hazards model, determined that an age difference between the recipient and donor was an independent risk factor (P = 0.03; hazard ratio, 7.395, 95% confidence interval, 1.2-46.7).This study showed that an age difference between the recipient and donor is an independent risk factor for mortality in patients who develop GvHD after LT." @default.
- W96676145 created "2016-06-24" @default.
- W96676145 creator A5009693893 @default.
- W96676145 creator A5025938906 @default.
- W96676145 creator A5059603524 @default.
- W96676145 date "2012-10-07" @default.
- W96676145 modified "2023-10-03" @default.
- W96676145 title "Graft-versus-host disease after liver transplantation: a comprehensive literature review." @default.
- W96676145 cites W129387772 @default.
- W96676145 cites W1964310484 @default.
- W96676145 cites W1964720811 @default.
- W96676145 cites W1970385611 @default.
- W96676145 cites W1971157111 @default.
- W96676145 cites W1973365962 @default.
- W96676145 cites W1976354599 @default.
- W96676145 cites W1981771806 @default.
- W96676145 cites W1983292759 @default.
- W96676145 cites W1983828864 @default.
- W96676145 cites W1984946393 @default.
- W96676145 cites W1985098471 @default.
- W96676145 cites W1988148764 @default.
- W96676145 cites W1993390264 @default.
- W96676145 cites W1994968709 @default.
- W96676145 cites W1995675450 @default.
- W96676145 cites W1996281179 @default.
- W96676145 cites W1998861308 @default.
- W96676145 cites W2000186562 @default.
- W96676145 cites W2000751446 @default.
- W96676145 cites W2003392903 @default.
- W96676145 cites W2004660649 @default.
- W96676145 cites W2007619627 @default.
- W96676145 cites W2008616803 @default.
- W96676145 cites W2011532073 @default.
- W96676145 cites W2012467376 @default.
- W96676145 cites W2017848406 @default.
- W96676145 cites W2018951808 @default.
- W96676145 cites W2019837522 @default.
- W96676145 cites W2019846107 @default.
- W96676145 cites W2026072940 @default.
- W96676145 cites W2026328986 @default.
- W96676145 cites W2032127324 @default.
- W96676145 cites W2040115767 @default.
- W96676145 cites W2041088942 @default.
- W96676145 cites W2043917672 @default.
- W96676145 cites W2044688083 @default.
- W96676145 cites W2047138860 @default.
- W96676145 cites W2050020936 @default.
- W96676145 cites W2051540664 @default.
- W96676145 cites W2058269677 @default.
- W96676145 cites W2061216348 @default.
- W96676145 cites W2061605100 @default.
- W96676145 cites W2063381533 @default.
- W96676145 cites W2065729726 @default.
- W96676145 cites W2072146924 @default.
- W96676145 cites W2074068803 @default.
- W96676145 cites W2078897109 @default.
- W96676145 cites W2085420960 @default.
- W96676145 cites W2086770234 @default.
- W96676145 cites W2091692444 @default.
- W96676145 cites W2092463172 @default.
- W96676145 cites W2092492099 @default.
- W96676145 cites W2093205694 @default.
- W96676145 cites W2103040140 @default.
- W96676145 cites W2106255909 @default.
- W96676145 cites W2107786006 @default.
- W96676145 cites W2115020299 @default.
- W96676145 cites W2135322861 @default.
- W96676145 cites W2151805507 @default.
- W96676145 cites W2170752033 @default.
- W96676145 cites W2259110239 @default.
- W96676145 cites W2305456283 @default.
- W96676145 cites W2337018256 @default.
- W96676145 cites W2412513152 @default.
- W96676145 cites W2415105497 @default.
- W96676145 cites W2466994663 @default.
- W96676145 cites W2471286732 @default.
- W96676145 cites W76269824 @default.
- W96676145 doi "https://doi.org/10.3748/wjg.v18.i37.5240" @default.
- W96676145 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3468857" @default.
- W96676145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23066319" @default.
- W96676145 hasPublicationYear "2012" @default.
- W96676145 type Work @default.
- W96676145 sameAs 96676145 @default.
- W96676145 citedByCount "15" @default.
- W96676145 countsByYear W966761452013 @default.
- W96676145 countsByYear W966761452014 @default.
- W96676145 countsByYear W966761452015 @default.
- W96676145 countsByYear W966761452016 @default.
- W96676145 countsByYear W966761452017 @default.
- W96676145 countsByYear W966761452019 @default.
- W96676145 countsByYear W966761452021 @default.
- W96676145 countsByYear W966761452022 @default.
- W96676145 countsByYear W966761452023 @default.
- W96676145 crossrefType "journal-article" @default.
- W96676145 hasAuthorship W96676145A5009693893 @default.
- W96676145 hasAuthorship W96676145A5025938906 @default.
- W96676145 hasAuthorship W96676145A5059603524 @default.
- W96676145 hasConcept C126322002 @default.
- W96676145 hasConcept C141071460 @default.
- W96676145 hasConcept C187212893 @default.