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- W96704428 abstract "While the ability of exercise to favorably influence bone mass and strength has been established long ago, the challenge becomes to determine which specific components of the loading milieu are anabolic and anti-resorptive to bone tissue and how to translate this information to the clinic. Loading parameters such as force magnitude, loading duration, or loading frequency all have a critical impact on altering the levels of bone formation and resorption and may interact with each other to define the skeletal outcome of any applied loading regime. Recent advances in understanding which components of bone’s mechanical milieu are osteogenic have allowed the development of biomechanical prophylaxes against bone loss, including the anabolic potential of extremely low-level, high-frequency mechanical signals, an example of a non-drug intervention for the prevention of bone loss. Studies such as these, while preliminary, emphasize that signals need not be large to be effective and that there may be ways of stimulating the skeleton mechanically without necessarily requiring an individual to exercise." @default.
- W96704428 created "2016-06-24" @default.
- W96704428 creator A5012957590 @default.
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- W96704428 date "2009-09-30" @default.
- W96704428 modified "2023-09-25" @default.
- W96704428 title "Mechanical Influences on Bone Mass and Morphology" @default.
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- W96704428 doi "https://doi.org/10.1007/978-1-59745-459-9_8" @default.
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