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• W967765340 abstract "Publisher Summary Trophoblastic diseases are classified histologically as hydatidiform mole, invasive mole and choriocarcinoma, and there were great differences between these diseases in their prognoses. Choriocarcinoma shows the characteristics of a malignant tumor. Therefore, the differential diagnosis is clinically important for the treatment of patients with trophoblastic diseases. To find out the qualitative difference between the human chorionic gonadotropin (hCG) produced by trophoblastic diseases and that produced in normal pregnancy a lot of work was done. Several investigators reported that the hCGs secreted by neoplastic trophoblasts, are more heterogeneous than that produced by normal trophoblasts, and suggested that the phenomenon is due to the alteration in their carbohydrate moiety. Such speculation, however, was presented on the basis of indirect works such as an examination of the discrepancy between bioactivity and immunoactivity, and difference in charge heterogeneity detected by means of pH gradient electrophoresis." @default.
• W967765340 created "2016-06-24" @default.
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• W967765340 date "1996-01-01" @default.
• W967765340 modified "2023-09-27" @default.
• W967765340 title "Chapter 3a Cancer cells and metastasis" @default.
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• W967765340 doi "https://doi.org/10.1016/s0167-7306(08)60285-9" @default.
• W967765340 hasPublicationYear "1996" @default.
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