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- W968864108 abstract "In pediatrics, the absorption of a perorally administered drug depends on the ability of the formulation to overcome the chemical, physical, mechanical, and biological barriers of the developing gastrointestinal tract. The differences between the pediatric and adult digestive systems are subtle, but physiologically important, and encompass organs from mouth to anus. Although the exact age of GI function maturation remains to be defined, clinically relevant developmental changes that influence drug absorption occur primarily during early childhood. This chapter reviews the developmental changes in gastrointestinal physiology that occur throughout childhood and discusses their relevance to formulation development and drug delivery." @default.
- W968864108 created "2016-06-24" @default.
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- W968864108 date "2014-01-01" @default.
- W968864108 modified "2023-10-16" @default.
- W968864108 title "General Considerations for Pediatric Oral Drug Formulation" @default.
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- W968864108 doi "https://doi.org/10.1007/978-1-4899-8011-3_7" @default.
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