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- W97054592 abstract "SUMMARY Humanthymocytes bindwithhumanredblood cells (HRBC)andneuraminidasetreated HRBC (nHRBC)forming rosettes. Peripheral bloodlymphocytes and tonsillar lymphocytes bindtonHRBCbutnotHRBC.Theconditions whichlead tonHRBCrosette formation aresimilar tothose required forrosette formation withsheep redbloodcells (SRBC). Therosetting ofhumanlymphocytes to nHRBCdoesnotrequire serumbutisprevented bypretreatment ofthelymphocytes withsodiumazide, proteolytic enzymes, 500Cfor7min,oranti-T cell (but notanti-B cell) serum. Peripheral lymphocytes frompatients withchronic lymphatic leukaemia donotrosette witheither HRBC ornHRBC.Therefore, the nHRBCrosetting lymphocyte isaliving T cell. Itisproposed thatthis invitro test maysimulate aninvivo mechanism forimmunesurveillance." @default.
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- W97054592 date "1973-11-01" @default.
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- W97054592 title "Rosetting of human red blood cells to thymocytes and thymus-derived cells." @default.
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