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- W971373670 abstract "This chapter is concerned with the use of steroids in the control of fertility in the woman. The chapter explores that no other development in steroid chemistry has had so great an impact upon the human imagination as the introduction of the contraceptive “pill”, which was first approved, as such, by the American Food and Drug Administration. This combination of steroids and variants thereof has been hailed by some as a major breakthrough in the control of population explosion and by others as bad medicine that should be banned pending further evaluation. The dominant role of the steroid chemist in contraception research, however, is now being slowly eroded by new developments involving entirely different types of chemical structure. The chapter discusses that the role of steroid hormones in the control of fertility has its origins in foetal biochemistry. Although the sex of the embryo is determined at the time of fertilization, it is impossible to distinguish between the male and female foetal gonads up to the 7th week of development. At this point the “indifferent gonad” begins the typical morphological changes that lead to its differentiation into the ovary or testis. The factors controlling this initial differentiation are unknown and there is no experimental evidence to show that steroids are involved." @default.
- W971373670 created "2016-06-24" @default.
- W971373670 creator A5013335229 @default.
- W971373670 date "1971-01-01" @default.
- W971373670 modified "2023-09-25" @default.
- W971373670 title "5 Antifertility Agents" @default.
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