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- W971827422 abstract "Publisher Summary This chapter presents the molecular studies of the radiation leukemia virus (RadLV) and related retroviruses of C57BL/Ka mice. RadLV denotes a class of slowly transforming viruses first isolated as a “leukemogenic activity” associated with cell-free extracts of thymic lymphomas that arose in C57BL/Ka mice, following fractionated whole-body X-irradiation. Several lines of evidence strongly suggest that the virus is the actual causative agent of these radiogenic lymphomas. A number of cell lines, designated as BL/RL, were derived from primary radiogenic lymphomas, and several other cell lines, designated as BL/VL, were derived from virus-induced lymphomas. BL/RL lines, when first established, are generally negative for virus production and the expression of viral antigens. The BL/VL lines are always positive for virus production. The viruses produced by two BL/RL lines and by two sublines of a BL/VL cell line, BL/VL 3 , have been analyzed at a molecular level using recombinant DNA technology and restriction enzyme mapping. These viruses are designated as RadLV/ RL 10 , RadLV/RL 15 , and RadLV/RL 3 . RadLV/VL 3 is a complex of several viruses." @default.
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- W971827422 date "1983-01-01" @default.
- W971827422 modified "2023-10-17" @default.
- W971827422 title "Molecular Studies of the Radiation Leukemia Virus (RadLV) and Related Retroviruses of C57BL/Ka Mice" @default.
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- W971827422 doi "https://doi.org/10.1016/s0079-6603(08)60431-6" @default.
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