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- W972154123 abstract "目的：检测哮喘患儿外周血髓系抑制细胞（MDSCs）、白细胞介素-10（IL-10）和白细胞介素-12（IL-12）的水平。方法：应用两色荧光标记技术流式细胞仪检测哮喘发作组（n=52）、哮喘缓解组（n=50）、肺炎对照组（n=45）及正常对照组（n=48）儿童外周血MDSCs,用双抗体夹心ELISA法检测血清IL-10、IL-12水平。结果：哮喘发作组较其他3组外周血MDSCs、血清IL-10水平升高,血清IL-12水平降低,差异有统计学意义（F=1043.820、1284.470和1139.380,P均〈0.05）;肺炎对照组与正常对照组各指标差异无统计学意义（P〉0.05）。哮喘发作组患儿外周血MDSCs水平与IL-10呈正相关（r=0.741,P=0.007）,与IL-12呈负相关（r=-0.879,P=0.014）。结论：MDSCs可能通过上调IL-10、下调IL-12在儿童哮喘发病中起作用。" @default.
- W972154123 created "2016-06-24" @default.
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- W972154123 date "2013-01-01" @default.
- W972154123 modified "2023-09-24" @default.
- W972154123 title "哮喘患儿外周血髓系抑制细胞、IL-10和IL-12水平检测" @default.
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