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- W972625612 abstract "Background: Epicardial ganglionated plexuses have recently become targets of both transcatheter and surgical ablative therapy of AF. The goal of this study was to determine the effects of biatrial epicardial, rather than endocardial, neuroablation on atrial refractoriness and AF induction in a chronic canine model of rapid atrial pacing (RAP). Methods: Fifteen canines underwent bilateral minithoracotomies with thoracoscopic guidance. Electrophysiological data was recorded in all dogs at baseline and following six weeks of RAP (400 bpm). Atrial effective refractory period (ERP) and AF inducibility were measured by decremental S1 pacing in the right (RAFW) and left (LAFW) atrial free walls and appendages. The ablation group (n=8) underwent excision of the right atrial and three left atrial ganglionated plexuses using an ultrasonic scalpel, thus assuring preservation of the underlying myocardium. The identical protocol was followed in the control group (n=7) without ganglionated plexus excision. Results: Aft..." @default.
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- W972625612 date "2011-11-22" @default.
- W972625612 modified "2023-09-28" @default.
- W972625612 title "Abstract 11481: Biatrial Epicardial Neuroablation Limits Atrial Fibrillation Susceptibility in a Canine Chronic Rapid Atrial Pacing Model" @default.
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